supp.fit

Zinc, Vitamin B12, Vitamin B6 and Folic Acid: study protocols

5 study groups took Zinc together with Vitamin B12, Vitamin B6 and Folic Acid. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

5 study groups in 5 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 10 mg to 25 mg, 40% of 5 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
2
25 mg to 50 mg
1

Dose per serving from research: Vitamin B12

5 study groups in 5 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 60% of 5 study groups.

Daily doseStudy groups
1 mcg or less
1
1 mcg to 2.5 mcg
0
2.5 mcg to 5 mcg
3
5 mcg to 10 mcg
1

Dose per serving from research: Vitamin B6

5 study groups in 5 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg and 2.5 mg to 5 mg, 40% of 5 study groups each.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
0
1 mg to 2.5 mg
2
2.5 mg to 5 mg
2

Dose per serving from research: Folic Acid

5 study groups in 5 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 60% of 5 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
1
250 mcg to 500 mcg
3
500 mcg to 1 mg
1

Commonly used together

5 of 5 study groups took Zinc, Vitamin B12, Vitamin B6 and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
4
Copper
3
Iodine
3
Riboflavin
3
Vitamin A
3
Vitamin C
3
Vitamin D
3
Vitamin E
3

5 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg2.6 mcg2.2 mg400 mcg——
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mg5.2 mcg2.6 mg400 mcg—870
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg2.6 mcg1.9 mg600 mcg—176
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg0.9 mcg500 mcg150 mcg22 weeks175
Nutraceutical approaches to homocysteine lowering in hypertensive subjects at low cardiovascular risk: a multicenter, randomized clinical trial
2016 · Normocis 400® group · Adults with stage 1 essential hypertension and hyper-homocysteinemia (HCys ≥15 μmol/L), without a history of cardiovascular or cerebrovascular disease; mean age 62.8 years, 63.5% male
12.5 mg5 mcg3 mg400 mcg60 days52