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Zinc, Vitamin B12 and Iron: study protocols

10 study groups took Zinc together with Vitamin B12 and Iron. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

10 study groups in 10 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 50% of 10 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
5
10 mg to 25 mg
2
25 mg to 50 mg
2

Dose per serving from research: Vitamin B12

9 study groups in 9 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 44% of 9 study groups.

Daily doseStudy groups
0.5 mcg to 1 mcg
3
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
4
over 5 mcg
1

Dose per serving from research: Iron

8 study groups in 8 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 50% of 8 study groups.

Daily doseStudy groups
5 mg to 10 mg
4
10 mg to 25 mg
1
25 mg to 50 mg
3

Commonly used together

10 of 10 study groups took Zinc, Vitamin B12 and Iron with something else. Shown: what 3 or more different studies gave. The 10 most common of 14.

What was given together, not what works together.

Taken withStudy groups
Vitamin A
9
Copper
7
Iodine
7
Vitamin B6
7
Vitamin C
7
Vitamin D
7
Vitamin E
7
Folic Acid
6
Niacin
4
Selenium
4

10 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg2.6 mcg———
Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa
2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers
10 mg0.9 mcg10 mg548 days—
Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial
2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania
10 mg———151
Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months
2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes
10 mg0.9 mcg10 mg548 days126
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mg5.2 mcg12 mg—870
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg2.6 mcg27 mg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg2.6 mcg27 mg—176
Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras
2014 · intervention group · Children enrolled at 5–18 months of age, living in rural Intibucá, Honduras, without stated medical conditions
27 mg2.7 mcg27 mg1 year160
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
4.2 mg1.35 mcg10 mg240 days—
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg0.9 mcg10 mg22 weeks175