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Zinc, Vitamin B12, Iron and Vitamin D: study protocols

7 study groups took Zinc together with Vitamin B12, Iron and Vitamin D. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

7 study groups in 7 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 57% of 7 study groups.

Daily doseStudy groups
5 mg to 10 mg
4
10 mg to 25 mg
2
over 25 mg
1

Dose per serving from research: Vitamin B12

6 study groups in 6 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 50% of 6 study groups.

Daily doseStudy groups
0.5 mcg to 1 mcg
2
1 mcg to 2.5 mcg
0
2.5 mcg to 5 mcg
3
over 5 mcg
1

Dose per serving from research: Iron

5 study groups in 5 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 25 mg to 50 mg, 40% of 5 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
2

Dose per serving from research: Vitamin D

6 study groups in 6 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 67% of 6 study groups.

Daily doseStudy groups
2.5 mcg to 5 mcg
4
5 mcg to 10 mcg
2

Commonly used together

7 of 7 study groups took Zinc, Vitamin B12, Iron and Vitamin D with something else. Shown: what 3 or more different studies gave. The 10 most common of 13.

What was given together, not what works together.

Taken withStudy groups
Copper
6
Iodine
6
Vitamin A
6
Vitamin B6
6
Vitamin C
6
Vitamin E
6
Folic Acid
4
Niacin
4
Vitamin K
4
Selenium
3

7 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg2.6 mcg—10 mcg——
Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa
2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers
10 mg0.9 mcg10 mg5 mcg548 days—
Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial
2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania
10 mg————151
Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months
2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes
10 mg0.9 mcg10 mg5 mcg548 days126
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mg5.2 mcg12 mg10 mcg—870
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg2.6 mcg27 mg5 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg2.6 mcg27 mg5 mcg—176