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Vitamin C and Folic Acid: study protocols

9 study groups took Vitamin C together with Folic Acid. These are the doses the studies gave. They are not a recommendation.

Vitamin C: what the research found →

Dose per serving from research: Vitamin C

9 study groups in 7 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 44% of 9 study groups.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
4
50 mg to 100 mg
2

Dose per serving from research: Folic Acid

9 study groups in 7 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg, 44% of 9 study groups.

Daily doseStudy groups
50 mcg to 100 mcg
1
100 mcg to 250 mcg
4
250 mcg to 500 mcg
2
500 mcg to 1 mg
0
1 mg to 2.5 mg
0
2.5 mg to 5 mg
0
5 mg to 10 mg
0
10 mg to 25 mg
0
25 mg to 50 mg
0
50 mg to 100 mg
2

Commonly used together

9 of 9 study groups took Vitamin C and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
8
Vitamin A
6
Vitamin B12
3
Zinc
3

9 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
100 mg400 mcg——
Low-dose B vitamins supplementation ameliorates cardiovascular risk: a double-blind randomized controlled trial in healthy Chinese elderly
2015 · treatment group · Healthy adults aged 60–74 years
50 mg400 mcg1 year—
The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial
2021 · Lp group · Healthy, non-anemic pregnant women aged 18–42 years, with singleton pregnancies and iron-replete status at enrollment
24 mg60 mcg—120
Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: a cluster-randomised trial
2006 · daily group · Children aged 3–6 years in a kindergarten in northern China
50 mg150 mcg13 weeks—
Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents
1997 · daily supplementation group · female Indonesian high-school adolescents
60 mg250 mcg90 days—
Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents
1997 · weekly supplementation group (60 mg Fe) · female Indonesian high-school adolescents
8.57 mg71.4 mg90 days—
Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents
1997 · weekly supplementation group (120 mg Fe) · female Indonesian high-school adolescents
8.57 mg71.4 mg90 days—
Micronutrient Sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural Haiti
2007 · Sprinkles-WSB (S-WSB) · Children aged 9–24 months in rural Haiti receiving take-home fortified wheat-soy blend rations
30 mg160 mcg60 days254
Efficacy and safety of emulsified microsomal ferric pyrophosphate vs. Ferrous Ascorbate in pregnancy with iron-deficiency anemia- a randomized, comparative study
2025 · Group A (test) · Pregnant women aged 20–35 years, at 13–16 weeks’ gestation, with iron-deficiency anemia (hemoglobin 9–10.5 g/dL and serum ferritin <15 mcg/L)
50 mg250 mcg4 weeks55
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