Vitamin C, Folic Acid and Iron: study protocols
8 study groups took Vitamin C together with Folic Acid and Iron. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin C
8 study groups in 6 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 38% of 8 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 1 |
| 25 mg to 50 mg | 3 |
| 50 mg to 100 mg | 2 |
Dose per serving from research: Folic Acid
8 study groups in 6 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 mcg to 250 mcg, 50% of 8 study groups.
| Daily dose | Study groups |
|---|---|
| 50 mcg to 100 mcg | 1 |
| 100 mcg to 250 mcg | 4 |
| 250 mcg to 500 mcg | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 0 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 0 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 0 |
| 50 mg to 100 mg | 2 |
Dose per serving from research: Iron
7 study groups in 5 studies say how much Iron participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg and 10 mg to 25 mg and 25 mg to 50 mg, 29% of 7 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 2 |
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 1 |
Commonly used together
8 of 8 study groups took Vitamin C, Folic Acid and Iron with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin A | 6 |
| Zinc | 3 |
8 study groups
| Study | |||||
|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 100 mg | 400 mcg | — | — | — |
| The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women: A randomized clinical trial 2021 · Lp group · Healthy, non-anemic pregnant women aged 18–42 years, with singleton pregnancies and iron-replete status at enrollment | 24 mg | 60 mcg | 8.4 mg | — | 120 |
| Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: a cluster-randomised trial 2006 · daily group · Children aged 3–6 years in a kindergarten in northern China | 50 mg | 150 mcg | 30 mg | 13 weeks | — |
| Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents 1997 · daily supplementation group · female Indonesian high-school adolescents | 60 mg | 250 mcg | 60 mg | 90 days | — |
| Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents 1997 · weekly supplementation group (60 mg Fe) · female Indonesian high-school adolescents | 8.57 mg | 71.4 mg | 8.57 mg | 90 days | — |
| Weekly micronutrient supplementation to build iron stores in female Indonesian adolescents 1997 · weekly supplementation group (120 mg Fe) · female Indonesian high-school adolescents | 8.57 mg | 71.4 mg | 17.1 mg | 90 days | — |
| Micronutrient Sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural Haiti 2007 · Sprinkles-WSB (S-WSB) · Children aged 9–24 months in rural Haiti receiving take-home fortified wheat-soy blend rations | 30 mg | 160 mcg | 12.5 mg | 60 days | 254 |
| Efficacy and safety of emulsified microsomal ferric pyrophosphate vs. Ferrous Ascorbate in pregnancy with iron-deficiency anemia- a randomized, comparative study 2025 · Group A (test) · Pregnant women aged 20–35 years, at 13–16 weeks’ gestation, with iron-deficiency anemia (hemoglobin 9–10.5 g/dL and serum ferritin <15 mcg/L) | 50 mg | 250 mcg | 27 mg | 4 weeks | 55 |