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Vitamin B12, Vitamin D, Iron and Vitamin B6: study protocols

6 study groups took Vitamin B12 together with Vitamin D, Iron and Vitamin B6. These are the doses the studies gave. They are not a recommendation.

Vitamin B12: what the research found →

Dose per serving from research: Vitamin B12

6 study groups in 5 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 50% of 6 study groups.

Daily doseStudy groups
1 mcg to 2.5 mcg
2
2.5 mcg to 5 mcg
3
over 5 mcg
1

Dose per serving from research: Vitamin D

5 study groups in 4 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 60% of 5 study groups.

Daily doseStudy groups
2.5 mcg to 5 mcg
3
5 mcg to 10 mcg
2

Dose per serving from research: Iron

5 study groups in 4 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 25 mg to 50 mg, 40% of 5 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
2

Dose per serving from research: Vitamin B6

6 study groups in 5 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 83% of 6 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
5
over 2.5 mg
1

Commonly used together

6 of 6 study groups took Vitamin B12, Vitamin D, Iron and Vitamin B6 with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Riboflavin
5
Folic Acid
4
Thiamine
4
Zinc
4
Copper
3
Iodine
3
Vitamin A
3
Vitamin C
3
Vitamin E
3

6 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
2.6 mcg10 mcg—2.2 mg——
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
5.2 mcg10 mcg12 mg2.6 mg—870
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
2.6 mcg5 mcg27 mg1.9 mg—176
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, morning · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
1.45 mcg4.15 mcg6.5 mg1.74 mg12 weeks18
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, evening · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
1.45 mcg4.15 mcg6.5 mg1.74 mg12 weeks16
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
2019 · UNIMMAP tablet · Nonpregnant, non-lactating healthy women aged 18–45 years in West Kiang, The Gambia; women of reproductive age with common micronutrient deficiencies in the population
2.6 mcg—30 mg1.9 mg12 weeks105