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Vitamin B12 and Vitamin A: study protocols

11 study groups took Vitamin B12 together with Vitamin A. These are the doses the studies gave. They are not a recommendation.

Vitamin B12: what the research found →

Dose per serving from research: Vitamin B12

11 study groups in 10 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 45% of 11 study groups.

Daily doseStudy groups
1 mcg or less
1
1 mcg to 2.5 mcg
2
2.5 mcg to 5 mcg
5
5 mcg to 10 mcg
0
10 mcg to 25 mcg
0
25 mcg to 50 mcg
1
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
0
500 mcg to 1 mg
0
1 mg to 2.5 mg
0
2.5 mg to 5 mg
0
5 mg to 10 mg
2

Dose per serving from research: Vitamin A

7 study groups in 7 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 57% of 7 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
2
500 mcg to 1 mg
4
1 mg to 2.5 mg
1

Commonly used together

11 of 11 study groups took Vitamin B12 and Vitamin A with something else. Shown: what 3 or more different studies gave. The 10 most common of 13.

What was given together, not what works together.

Taken withStudy groups
Folic Acid
10
Iron
9
Zinc
8
Vitamin E
7
Copper
6
Vitamin B6
6
Vitamin C
6
Iodine
5
Selenium
5
Vitamin D
5

11 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
2.6 mcg1 mg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women
50 mcg5,000 IU——
Associations of maternal nutrition during pregnancy and post-partum with maternal cognition and caregiving
2018 · MMN · Pregnant women enrolled at ≤20 weeks’ gestation in Malawi, followed through 6 months postpartum
5.2 mg—1 year239
Associations of maternal nutrition during pregnancy and post-partum with maternal cognition and caregiving
2018 · LNS · Pregnant women enrolled at ≤20 weeks’ gestation in Malawi, followed through 6 months postpartum
5.2 mg—1 year234
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
2.6 mcg770 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
2.6 mcg770 mcg—176
Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras
2014 · intervention group · Children enrolled at 5–18 months of age, living in rural Intibucá, Honduras, without stated medical conditions
2.7 mcg1.2 mg1 year160
Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial
2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies
0.9 mcg400 mcg36 weeks130
Multiple micronutrient supplementation improves vitamin B₁₂ and folate concentrations of HIV infected children in Uganda: a randomized controlled trial
2011 · Multiple micronutrient supplementation (MMS) · HIV-infected children aged 1–5 years
2.4 mcg800 mcg26 weeks104
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
1.35 mcg375 mcg240 days—