supp.fit

Vitamin B12, Folic Acid and Vitamin A: study protocols

10 study groups took Vitamin B12 together with Folic Acid and Vitamin A. These are the doses the studies gave. They are not a recommendation.

Vitamin B12: what the research found →

Dose per serving from research: Vitamin B12

10 study groups in 9 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 40% of 10 study groups.

Daily doseStudy groups
1 mcg or less
1
1 mcg to 2.5 mcg
2
2.5 mcg to 5 mcg
4
5 mcg to 10 mcg
0
10 mcg to 25 mcg
0
25 mcg to 50 mcg
1
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
0
500 mcg to 1 mg
0
1 mg to 2.5 mg
0
2.5 mg to 5 mg
0
5 mg to 10 mg
2

Dose per serving from research: Folic Acid

10 study groups in 9 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 40% of 10 study groups.

Daily doseStudy groups
50 mcg or less
1
50 mcg to 100 mcg
0
100 mcg to 250 mcg
2
250 mcg to 500 mcg
4
500 mcg to 1 mg
3

Dose per serving from research: Vitamin A

6 study groups in 6 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 67% of 6 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
2
500 mcg to 1 mg
4

Commonly used together

10 of 10 study groups took Vitamin B12, Folic Acid and Vitamin A with something else. Shown: what 3 or more different studies gave. The 10 most common of 12.

What was given together, not what works together.

Taken withStudy groups
Iron
8
Vitamin E
7
Zinc
7
Copper
6
Vitamin B6
6
Vitamin C
6
Iodine
5
Selenium
5
Vitamin D
5
Niacin
4

10 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
2.6 mcg400 mcg1 mg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women
50 mcg800 mcg5,000 IU——
Associations of maternal nutrition during pregnancy and post-partum with maternal cognition and caregiving
2018 · MMN · Pregnant women enrolled at ≤20 weeks’ gestation in Malawi, followed through 6 months postpartum
5.2 mg400 mcg—1 year239
Associations of maternal nutrition during pregnancy and post-partum with maternal cognition and caregiving
2018 · LNS · Pregnant women enrolled at ≤20 weeks’ gestation in Malawi, followed through 6 months postpartum
5.2 mg400 mcg—1 year234
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
2.6 mcg600 mcg770 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
2.6 mcg600 mcg770 mcg—176
Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial
2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies
0.9 mcg150 mcg400 mcg36 weeks130
Multiple micronutrient supplementation improves vitamin B₁₂ and folate concentrations of HIV infected children in Uganda: a randomized controlled trial
2011 · Multiple micronutrient supplementation (MMS) · HIV-infected children aged 1–5 years
2.4 mcg40 mcg800 mcg26 weeks104
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
1.35 mcg225 mcg375 mcg240 days—
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
2019 · UNIMMAP tablet · Nonpregnant, non-lactating healthy women aged 18–45 years in West Kiang, The Gambia; women of reproductive age with common micronutrient deficiencies in the population
2.6 mcg400 mcg—12 weeks105