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Vitamin A, Zinc, Iron and Folic Acid: study protocols

10 study groups took Vitamin A together with Zinc, Iron and Folic Acid. These are the doses the studies gave. They are not a recommendation.

Vitamin A: what the research found →

Dose per serving from research: Vitamin A

10 study groups in 8 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 60% of 10 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
4
500 mcg to 1 mg
6

Dose per serving from research: Zinc

10 study groups in 8 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 40% of 10 study groups.

Daily doseStudy groups
2.5 mg to 5 mg
3
5 mg to 10 mg
1
10 mg to 25 mg
2
25 mg to 50 mg
4

Dose per serving from research: Iron

9 study groups in 8 studies say how much Iron participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg and 50 mg to 100 mg, 33% of 9 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
3
50 mg to 100 mg
3

Dose per serving from research: Folic Acid

10 study groups in 8 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg and 250 mcg to 500 mcg, 40% of 10 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
4
250 mcg to 500 mcg
4
500 mcg to 1 mg
2

Commonly used together

8 of 10 study groups took Vitamin A, Zinc, Iron and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin C
6
Vitamin B12
5
Copper
4
Vitamin E
4
Iodine
3
Selenium
3
Vitamin B6
3
Vitamin D
3

10 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Folic acid + iron + zinc · Pregnant women in rural Nepal
1 mg30 mg60 mg400 mcg——
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
1 mg30 mg—400 mcg——
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
770 mcg12 mg27 mg600 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
770 mcg12 mg27 mg600 mcg—176
Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: a cluster-randomised trial
2006 · daily group · Children aged 3–6 years in a kindergarten in northern China
300 mcg5 mg30 mg150 mcg13 weeks—
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
375 mcg4.2 mg10 mg225 mcg240 days—
Micronutrient Sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural Haiti
2007 · Sprinkles-WSB (S-WSB) · Children aged 9–24 months in rural Haiti receiving take-home fortified wheat-soy blend rations
400 mcg5 mg12.5 mg160 mcg60 days254
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
400 mcg10 mg10 mg150 mcg22 weeks175
Supplementation with micronutrients in addition to iron and folic acid does not further improve the hematologic status of pregnant women in rural Nepal
2003 · folic acid plus iron and zinc · Pregnant women in rural Nepal
1 mg30 mg60 mg400 mcg——
Supplementation with micronutrients in addition to iron and folic acid does not further improve the hematologic status of pregnant women in rural Nepal
2003 · folic acid plus iron, zinc and multiple micronutrients · Pregnant women in rural Nepal
1 mg30 mg60 mg400 mcg——