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Vitamin A and Vitamin B12: study protocols

9 study groups took Vitamin A together with Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Vitamin A: what the research found →

Dose per serving from research: Vitamin A

6 study groups in 6 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 50% of 6 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
2
500 mcg to 1 mg
3
1 mg to 2.5 mg
1

Dose per serving from research: Vitamin B12

9 study groups in 9 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 44% of 9 study groups.

Daily doseStudy groups
0.5 mcg to 1 mcg
3
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
4
5 mcg to 10 mcg
0
10 mcg to 25 mcg
0
25 mcg to 50 mcg
1

Commonly used together

9 of 9 study groups took Vitamin A and Vitamin B12 with something else. Shown: what 3 or more different studies gave. The 10 most common of 14.

What was given together, not what works together.

Taken withStudy groups
Iron
8
Zinc
8
Vitamin C
7
Vitamin E
7
Copper
6
Folic Acid
6
Vitamin B6
6
Iodine
5
Vitamin D
5
Niacin
3

9 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
1 mg2.6 mcg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women
5,000 IU50 mcg——
Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa
2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers
1,250 IU0.9 mcg548 days—
Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months
2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes
1,250 IU0.9 mcg548 days126
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
770 mcg2.6 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
770 mcg2.6 mcg—176
Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras
2014 · intervention group · Children enrolled at 5–18 months of age, living in rural Intibucá, Honduras, without stated medical conditions
1.2 mg2.7 mcg1 year160
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
375 mcg1.35 mcg240 days—
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
400 mcg0.9 mcg22 weeks175