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Vitamin A, Folic Acid and Vitamin B12: study protocols

6 study groups took Vitamin A together with Folic Acid and Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Vitamin A: what the research found →

Dose per serving from research: Vitamin A

5 study groups in 5 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 60% of 5 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
2
500 mcg to 1 mg
3

Dose per serving from research: Folic Acid

6 study groups in 6 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 50% of 6 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
2
250 mcg to 500 mcg
1
500 mcg to 1 mg
3

Dose per serving from research: Vitamin B12

6 study groups in 6 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 50% of 6 study groups.

Daily doseStudy groups
1 mcg or less
1
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
3
5 mcg to 10 mcg
0
10 mcg to 25 mcg
0
25 mcg to 50 mcg
1

Commonly used together

6 of 6 study groups took Vitamin A, Folic Acid and Vitamin B12 with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
5
Vitamin C
5
Vitamin E
5
Zinc
5
Copper
4
Vitamin B6
4
Iodine
3
Selenium
3
Vitamin D
3

6 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
1 mg400 mcg2.6 mcg——
Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension
2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women
5,000 IU800 mcg50 mcg——
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
770 mcg600 mcg2.6 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
770 mcg600 mcg2.6 mcg—176
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
375 mcg225 mcg1.35 mcg240 days—
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
400 mcg150 mcg0.9 mcg22 weeks175