Riboflavin, Niacin, Vitamin B12 and Vitamin E: study protocols
5 study groups took Riboflavin together with Niacin, Vitamin B12 and Vitamin E. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Riboflavin
5 study groups in 5 studies say how much Riboflavin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 60% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 500 mcg or less | 1 |
| 500 mcg to 1 mg | 0 |
| 1 mg to 2.5 mg | 3 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 0 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 0 |
| 50 mg to 100 mg | 0 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 1 |
Dose per serving from research: Niacin
5 study groups in 5 studies say how much Niacin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 80% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 4 |
Dose per serving from research: Vitamin B12
5 study groups in 5 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 2.5 mcg to 5 mcg, 40% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 1 mcg or less | 1 |
| 1 mcg to 2.5 mcg | 1 |
| 2.5 mcg to 5 mcg | 2 |
| 5 mcg to 10 mcg | 1 |
Dose per serving from research: Vitamin E
5 study groups in 5 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg, 60% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 0 |
| 50 mg to 100 mg | 0 |
| 100 mg to 250 mg | 1 |
Commonly used together
5 of 5 study groups took Riboflavin, Niacin, Vitamin B12 and Vitamin E with something else. Shown: what 3 or more different studies gave. The 10 most common of 11.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Copper | 5 |
| Iron | 5 |
| Vitamin A | 5 |
| Vitamin B6 | 5 |
| Zinc | 5 |
| Folic Acid | 4 |
| Thiamine | 4 |
| Vitamin C | 4 |
| Vitamin D | 4 |
| Iodine | 3 |
5 study groups
| Study | ||||||
|---|---|---|---|---|---|---|
| Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren 2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified | 1.6 mg | 16 mg | 2 mcg | 8 mg | 335 days | — |
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 1.8 mg | 20 mg | 2.6 mcg | 10 mg | — | — |
| Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial 2015 · Verum (investigational nutritional product) · Adults aged 18–65 of either sex with migraine with or without aura, and at least 3 migraine attacks per month before recruitment | 400 mg | 20 mg | 6 mcg | 134 mg | 90 days | 63 |
| Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B(12) status among young Laotian children: a randomized controlled trial 2022 · micronutrient powder group (MNP) · Children aged 6–23 months in rural Lao PDR; no disease-based selection, with high prevalence of undernutrition and micronutrient deficiencies | 500 mcg | 6 mg | 0.9 mcg | 5 mg | 36 weeks | 130 |
| A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia 2019 · UNIMMAP tablet · Nonpregnant, non-lactating healthy women aged 18–45 years in West Kiang, The Gambia; women of reproductive age with common micronutrient deficiencies in the population | 1.4 mg | 18 mg | 2.6 mcg | 10 mg | 12 weeks | 105 |