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Omega-3 Fatty Acids and Vitamin C: study protocols

17 study groups took Omega-3 Fatty Acids together with Vitamin C. These are the doses the studies gave. They are not a recommendation.

Omega-3 Fatty Acids: what the research found →

Dose per serving from research: Omega-3 Fatty Acids

17 study groups in 15 studies say how much Omega-3 Fatty Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g and 1 g to 2.5 g, 29% of 17 study groups each.

Daily doseStudy groups
100 mg to 250 mg
2
250 mg to 500 mg
3
500 mg to 1 g
5
1 g to 2.5 g
5
2.5 g to 5 g
2

Dose per serving from research: Vitamin C

15 study groups in 14 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 33% of 15 study groups.

Daily doseStudy groups
50 mg to 100 mg
5
100 mg to 250 mg
2
250 mg to 500 mg
4
500 mg to 1 g
4

Commonly used together

16 of 17 study groups took Omega-3 Fatty Acids and Vitamin C with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin E
11
Zinc
7
Vitamin A
6
Copper
5
Selenium
4
Beta-Carotene
3

17 study groups

Study
A randomized controlled trial to prevent post-operative atrial fibrillation by antioxidant reinforcement
2013 · supplemented group · Patients scheduled for on-pump cardiac surgery; age and sex not specified
2 g1 g—103
TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD
2007 · Sham MCS and nutritional supplement · Adults aged 50–90 with dry age-related macular degeneration in at least one eye
300 mg452 mg24 weeks37
A randomized, double-masked study to evaluate the effect of omega-3 fatty acids supplementation in meibomian gland dysfunction
2013 · Group B (study oral supplement formulation, Brudysec 1.5 g) · Adults aged 23–85 years, both sexes, diagnosed with meibomian gland dysfunction
1.27 g80.1 mg90 days33
Effect of a 12-mo micronutrient intervention on learning and memory in well-nourished and marginally nourished school-aged children: 2 parallel, randomized, placebo-controlled studies in Australia and Indonesia
2007 · Australia micronutrient mix plus DHA+EPA · Children aged 6–10 years in Australia, described as well-nourished
110 mg—1 year—
Effect of a 12-mo micronutrient intervention on learning and memory in well-nourished and marginally nourished school-aged children: 2 parallel, randomized, placebo-controlled studies in Australia and Indonesia
2007 · Indonesia micronutrient mix plus DHA+EPA · Children aged 6–10 years in Indonesia, described as marginally nourished
110 mg—1 year—
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders
2013 · DEDG+S · Adults aged 23–80 years, both sexes, with mild-to-moderate dry eye disorders
845 mg53.4 mg90 days—
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders
2013 · CG+S · Healthy adults aged 23–80 years, both sexes
845 mg53.4 mg90 days—
Supplemental Protein and a Multinutrient Beverage Speed Wound Healing after Acute Sleep Restriction in Healthy Adults
2022 · NUT · Generally healthy young adults aged 18–approximately 20 years (18 males and 2 females), after acute sleep restriction
1 g400 mg7 days—
Comparison of the effects of simultaneous administration of vitamin C and omega-3 fatty acids on lipoproteins, apo A-I, apo B, and malondialdehyde in hyperlipidemic patients
2003 · VitC + n-3FAs group · Hyperlipidemic patients with total cholesterol and triglycerides greater than 200 mg/dL; age and sex not specified
1 g500 mg10 weeks—
Effects of eicosapentaenoic acid supplementation in the treatment of chronic hepatitis C patients
2005 · EPA group · Patients with chronic hepatitis C receiving interferon alpha-2b and ribavirin; age and sex not reported
1.8 g600 mg24 weeks5
Antioxidant therapy reduces oxidative and inflammatory tissue damage in patients subjected to cardiac surgery with extracorporeal circulation
2011 · n-3 PUFA plus antioxidant vitamins · Either-sex patients undergoing on-pump cardiac surgery
2 g1 g——
Effect of mixed flavonoids, n-3 fatty acids, and vitamin C on oxidative stress and antioxidant capacity before and after intense cycling
2011 · QFO · Athletes; age and sex not specified
400 mg1 g17 days—
The medical food Souvenaid affects brain phospholipid metabolism in mild Alzheimer's disease: results from a randomized controlled trial
2017 · Test product (Souvenaid/Fortasyn Connect) · Adults aged 50 years or older with mild probable or possible Alzheimer’s disease
300 mg80 mg4 weeks16
Omega-3 supplementation combined with anti-vascular endothelial growth factor lowers vitreal levels of vascular endothelial growth factor in wet age-related macular degeneration
2014 · Group 1 (Vitalux plus Omega-3) · Adults with active wet age-related macular degeneration who had previously received anti-VEGF treatment
1.05 g500 mg—10
Effects of 6 weeks of n-3 fatty acids and antioxidant mixture on lipid peroxidation at rest and postexercise
2011 · LCPUFA plus antioxidant mixture · Judoists; age and sex not reported; no diagnosed condition stated
1 g60 mg6 weeks—
Peroxidation of LDL from combined-hyperlipidemic male smokers supplied with omega-3 fatty acids and antioxidants
1997 · omega-3 FAs and antioxidants · male smokers with combined hyperlipidemia
5 g150 mg6 weeks—
Effects of omega-3 fatty acids and/or antioxidants on endothelial cell markers
1998 · n-3 fatty acids with antioxidants · adult male smokers with hyperlipidaemia
4.8 g150 mg6 weeks—
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