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Omega-3 Fatty Acids, Vitamin C and Vitamin E: study protocols

11 study groups took Omega-3 Fatty Acids together with Vitamin C and Vitamin E. These are the doses the studies gave. They are not a recommendation.

Omega-3 Fatty Acids: what the research found →

Dose per serving from research: Omega-3 Fatty Acids

11 study groups in 10 studies say how much Omega-3 Fatty Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 45% of 11 study groups.

Daily doseStudy groups
500 mg or less
1
500 mg to 1 g
3
1 g to 2.5 g
5
2.5 g to 5 g
2

Dose per serving from research: Vitamin C

11 study groups in 10 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 36% of 11 study groups.

Daily doseStudy groups
50 mg to 100 mg
4
100 mg to 250 mg
2
250 mg to 500 mg
2
500 mg to 1 g
3

Dose per serving from research: Vitamin E

7 study groups in 6 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 50 mg to 100 mg, 29% of 7 study groups each.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
1
50 mg to 100 mg
2
100 mg to 250 mg
0
over 250 mg
1

Commonly used together

8 of 11 study groups took Omega-3 Fatty Acids, Vitamin C and Vitamin E with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Copper
5
Zinc
5
Vitamin A
4
Beta-Carotene
3

11 study groups

Study
A randomized controlled trial to prevent post-operative atrial fibrillation by antioxidant reinforcement
2013 · supplemented group · Patients scheduled for on-pump cardiac surgery; age and sex not specified
2 g1 g400 IU—103
TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD
2007 · Sham MCS and nutritional supplement · Adults aged 50–90 with dry age-related macular degeneration in at least one eye
300 mg452 mg200 IU24 weeks37
A randomized, double-masked study to evaluate the effect of omega-3 fatty acids supplementation in meibomian gland dysfunction
2013 · Group B (study oral supplement formulation, Brudysec 1.5 g) · Adults aged 23–85 years, both sexes, diagnosed with meibomian gland dysfunction
1.27 g80.1 mg12 mg90 days33
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders
2013 · DEDG+S · Adults aged 23–80 years, both sexes, with mild-to-moderate dry eye disorders
845 mg53.4 mg8 mg90 days—
Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflammation and immune response mediators in tears from patients with dry eye disorders
2013 · CG+S · Healthy adults aged 23–80 years, both sexes
845 mg53.4 mg8 mg90 days—
Effects of eicosapentaenoic acid supplementation in the treatment of chronic hepatitis C patients
2005 · EPA group · Patients with chronic hepatitis C receiving interferon alpha-2b and ribavirin; age and sex not reported
1.8 g600 mg300 mg24 weeks5
Antioxidant therapy reduces oxidative and inflammatory tissue damage in patients subjected to cardiac surgery with extracorporeal circulation
2011 · n-3 PUFA plus antioxidant vitamins · Either-sex patients undergoing on-pump cardiac surgery
2 g1 g400 IU——
Omega-3 supplementation combined with anti-vascular endothelial growth factor lowers vitreal levels of vascular endothelial growth factor in wet age-related macular degeneration
2014 · Group 1 (Vitalux plus Omega-3) · Adults with active wet age-related macular degeneration who had previously received anti-VEGF treatment
1.05 g500 mg400 IU—10
Effects of 6 weeks of n-3 fatty acids and antioxidant mixture on lipid peroxidation at rest and postexercise
2011 · LCPUFA plus antioxidant mixture · Judoists; age and sex not reported; no diagnosed condition stated
1 g60 mg30 mg6 weeks—
Peroxidation of LDL from combined-hyperlipidemic male smokers supplied with omega-3 fatty acids and antioxidants
1997 · omega-3 FAs and antioxidants · male smokers with combined hyperlipidemia
5 g150 mg75 mg6 weeks—
Effects of omega-3 fatty acids and/or antioxidants on endothelial cell markers
1998 · n-3 fatty acids with antioxidants · adult male smokers with hyperlipidaemia
4.8 g150 mg75 mg6 weeks—
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