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Magnesium and Vitamin D: study protocols

14 study groups took Magnesium together with Vitamin D. These are the doses the studies gave. They are not a recommendation.

Magnesium: what the research found →

Dose per serving from research: Magnesium

13 study groups in 12 studies say how much Magnesium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 38% of 13 study groups.

Daily doseStudy groups
50 mg or less
1
50 mg to 100 mg
4
100 mg to 250 mg
5
250 mg to 500 mg
1
500 mg to 1 g
1
over 1 g
1

Dose per serving from research: Vitamin D

8 study groups in 8 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 IU to 500 IU, 50% of 8 study groups.

Daily doseStudy groups
250 IU to 500 IU
4
500 IU to 1,000 IU
0
1,000 IU to 2,500 IU
0
2,500 IU to 5,000 IU
1
5,000 IU to 10,000 IU
3

Commonly used together

10 of 14 study groups took Magnesium and Vitamin D with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Zinc
9
Calcium
8

14 study groups

Study
Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
2015 · Verum (investigational nutritional product) · Adults aged 18–65 of either sex with migraine with or without aura, and at least 3 migraine attacks per month before recruitment
600 mg5 mcg90 days63
The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial
2021 · Intervention group · Children aged 6–12 years with ADHD and low serum 25-hydroxyvitamin D and magnesium levels
6 mg/kg7,143 IU8 weeks33
Randomized study of the effects of vitamin D and/or magnesium supplementation on mood, serum levels of BDNF, inflammation, and SIRT1 in obese women with mild to moderate depressive symptoms
2022 · co-supplementation group · Obese women with mild to moderate depressive symptoms
250 mg7,143 IU8 weeks27
Randomized Study of the Effects of Vitamin D and Magnesium Co-Supplementation on Muscle Strength and Function, Body Composition, and Inflammation in Vitamin D-Deficient Middle-Aged Women
2021 · intervention · Women aged 40–55 years with vitamin D deficiency
250 mg7,143 IU8 weeks—
Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause
2006 · ES (Estromineral serena) · Symptomatic menopausal women with sleep or mood alterations
50 mg—24 weeks44
Magnesium-Zinc-Calcium-Vitamin D Co-supplementation Improves Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
2018 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS); age not reported
200 mg400 IU12 weeks30
Supportive treatment of vascular dysfunction in pediatric subjects with obesity: the OBELIX study
2022 · Treatment group · Children aged 6–17 years with obesity (BMI above the 95th percentile for age)
300 mg25 mcg26 weeks16
[Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter trial]
2004 · Group 1: Vitrum Osteomag · Postmenopausal women with osteopenia; age range not reported
80 mg400 IU1 year125
Calcium and vitamin D fortified milk reduces bone turnover and improves bone density in postmenopausal women over 1 year
2018 · intervention · Chinese postmenopausal women in Malaysia; mean age 59 years
96 mg15 mcg1 year61
The effect of combined magnesium and vitamin D supplementation on vitamin D status, systemic inflammation, and blood pressure: A randomized double-blinded controlled trial
2022 · magnesium + vitamin D (MagD) · Overweight or obese participants; age and sex not reported
1.08 g3,000 IU12 weeks—
A Trial on The Effects of Magnesium-Zinc-Calcium-Vitamin D Co-Supplementation on Glycemic Control and Markers of Cardio-Metabolic Risk in Women with Polycystic Ovary Syndrome
2017 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS)
200 mg400 IU12 weeks30
The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes
2019 · Magnesium-zinc-calcium-vitamin D group · Women aged 18–40 with gestational diabetes mellitus, at 24–28 weeks’ gestation at diagnosis
200 mg400 IU6 weeks30
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), premenopausal women · Premenopausal women, mean age 41 years; no specific condition stated
96 mg15 mcg12 weeks—
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), postmenopausal women · Postmenopausal women, mean age 59 years; no specific condition stated
96 mg15 mcg12 weeks—
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