Magnesium and Vitamin B6: study protocols
10 study groups took Magnesium together with Vitamin B6. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Magnesium
10 study groups in 9 studies say how much Magnesium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mg to 500 mg, 40% of 10 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mg to 250 mg | 3 |
| 250 mg to 500 mg | 4 |
| 500 mg to 1 g | 1 |
| 1 g to 2.5 g | 2 |
Dose per serving from research: Vitamin B6
10 study groups in 9 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 40% of 10 study groups.
| Daily dose | Study groups |
|---|---|
| 2.5 mg or less | 1 |
| 2.5 mg to 5 mg | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 4 |
| 25 mg to 50 mg | 3 |
Commonly used together
4 of 10 study groups took Magnesium and Vitamin B6 with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin B12 | 3 |
| Vitamin C | 3 |
10 study groups
| Study | ||||
|---|---|---|---|---|
| A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study 2000 · 200 mg Mg + 50 mg vitamin B6 · Women with mild premenstrual symptoms, average age 32 years | 200 mg | 50 mg | — | 44 |
| Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial 2021 · Magnesium + vitamin B6 · Adults aged 18–50 with moderate to extremely severe stress and suboptimal serum magnesium levels | 300 mg | 30 mg | 8 weeks | 132 |
| Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial 2015 · Verum (investigational nutritional product) · Adults aged 18–65 of either sex with migraine with or without aura, and at least 3 migraine attacks per month before recruitment | 600 mg | 5 mg | 90 days | 63 |
| Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial 2018 · Mg–vitamin B6 combination · Adults aged 18–50 with moderate to extremely severe stress and suboptimal serum magnesium concentrations | 1.41 g | 15 mg | 8 weeks | 132 |
| Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals-A Randomized, Placebo-Controlled Study 2022 · Mg-Teadiola · Adults aged 18–65, either sex, otherwise healthy and chronically stressed (DASS-42 stress score ≥14) | 150 mg | 700 mcg | 4 weeks | 51 |
| A Magtein(®), Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults 2022 · Magtein®PS group · Healthy Chinese adults aged 18–65 years, men and women | 1.6 g | 16 mg | 30 days | 51 |
| Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation 2011 · Group MVB · Patients with type 2 diabetes | 250 mg | 10 mg | 120 days | — |
| Impact of magnesium supplementation, in combination with vitamin B6, on stress and magnesium status: secondary data from a randomized controlled trial 2020 · Magnesium-vitamin B6 · Adults with stress; the erythrocyte-magnesium subgroup analysis included participants with low baseline erythrocyte magnesium (<1.6 mmol/L). | 300 mg | 30 mg | 8 weeks | 132 |
| Prospective Randomized Evaluation of Idiopathic Hyperoxaluria Treatments 2021 · low oxalate diet and supplementation (DS) · Patients with a documented history of calcium oxalate stones and newly diagnosed idiopathic hyperoxaluria | 400 mg | 25 mg | 12 weeks | 55 |
| Prospective Randomized Evaluation of Idiopathic Hyperoxaluria Treatments 2021 · supplementation (S) · Patients with a documented history of calcium oxalate stones and newly diagnosed idiopathic hyperoxaluria | 400 mg | 25 mg | 12 weeks | 47 |