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Magnesium and Calcium: study protocols

24 study groups took Magnesium together with Calcium. These are the doses the studies gave. They are not a recommendation.

Magnesium: what the research found →

Dose per serving from research: Magnesium

22 study groups in 17 studies say how much Magnesium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 36% of 22 study groups.

Daily doseStudy groups
50 mg or less
1
50 mg to 100 mg
7
100 mg to 250 mg
8
250 mg to 500 mg
3
500 mg to 1 g
3

Dose per serving from research: Calcium

21 study groups in 16 studies say how much Calcium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 g to 2.5 g, 57% of 21 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
3
500 mg to 1 g
5
1 g to 2.5 g
12

Commonly used together

16 of 24 study groups took Magnesium and Calcium with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin D
8
Zinc
7

24 study groups

Study
Impact of Preoperative Calcium and Magnesium Supplementation on Quality of Life and Hypocalcemia Post-Thyroidectomy
2026 · Intervention group A · Adults aged 20–70 with Graves’ disease or nodular goitre undergoing thyroidectomy
375 mg—2 weeks40
Gaviscon Double Action Liquid (antacid & alginate) is more effective than antacid in controlling post-prandial oesophageal acid exposure in GERD patients: a double-blind crossover study
2014 · CVS Antacid Supreme · Adults with GERD symptoms and a history of LA A or B esophagitis and/or abnormal pH monitoring
135 mg400 mg1 day—
Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause
2006 · ES (Estromineral serena) · Symptomatic menopausal women with sleep or mood alterations
50 mg141 mg24 weeks44
Magnesium-Zinc-Calcium-Vitamin D Co-supplementation Improves Hormonal Profiles, Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial
2018 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS); age not reported
200 mg800 mg12 weeks30
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
2017 · Control · Postmenopausal women with osteopenia; age range not stated
550 mg1.2 g1 year—
Effect on blood pressure of potassium, calcium, and magnesium in women with low habitual intake
1998 · all three minerals together · Normotensive women, mean age 39, with low habitual intake of potassium, calcium, and magnesium
14 mmol30 mmol16 weeks—
Effect of lactulose on calcium and magnesium absorption: a study using stable isotopes in adult men
2007 · low-dose lactulose (2 g) · 24 healthy adult men
150 mg300 mg1 day24
Effect of lactulose on calcium and magnesium absorption: a study using stable isotopes in adult men
2007 · high-dose lactulose (4 g) · 24 healthy adult men
150 mg300 mg1 day24
[Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter trial]
2004 · Group 1: Vitrum Osteomag · Postmenopausal women with osteopenia; age range not reported
80 mg1.2 g1 year125
Calcium and vitamin D fortified milk reduces bone turnover and improves bone density in postmenopausal women over 1 year
2018 · intervention · Chinese postmenopausal women in Malaysia; mean age 59 years
96 mg1.2 g1 year61
Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial
2017 · RCE · Postmenopausal women with osteopenia; age range not stated
550 mg1.2 g1 year—
Negative balance of calcium and magnesium under relatively low sodium intake in humans
2003 · Relatively low sodium intake with adequate calcium and magnesium intake · Six female students; ages and health status not reported
280 mg800 mg10 days6
Small bowel absorption of magnesium and calcium sulphate from a natural mineral water in subjects with ileostomy
2006 · High-mineral-content natural mineral water · Six subjects with ileostomy
2.3 mmol6.9 mmol2 days6
Impact of supplementary high calcium milk with additional magnesium on parathyroid hormone and biochemical markers of bone turnover in postmenopausal women
2002 · milk group · Healthy postmenopausal women
106 mg1.2 g4 weeks25
Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption
2003 · HCSM with 65.5 mg magnesium · Healthy postmenopausal women
65.5 mg1.2 g1 day21
Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption
2003 · HCSM with 172 mg magnesium · Healthy postmenopausal women
172 mg1.2 g1 day21
MgCaCO3 versus CaCO3 in peritoneal dialysis patients--a cross-over pilot trial
2015 · MgCaCO3 group · Adults with peritoneal dialysis
965 mg1.14 g90 days—
Magnesium carbonate as a phosphorus binder: a prospective, controlled, crossover study
1996 · MgCO3 plus half the usual dose of CaCO3 · Chronic hemodialysis patients
465 mg1.2 g——
A Trial on The Effects of Magnesium-Zinc-Calcium-Vitamin D Co-Supplementation on Glycemic Control and Markers of Cardio-Metabolic Risk in Women with Polycystic Ovary Syndrome
2017 · Magnesium-zinc-calcium-vitamin D co-supplementation · Women with polycystic ovary syndrome (PCOS)
200 mg800 mg12 weeks30
The effects of magnesium-zinc-calcium-vitamin D co-supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes
2019 · Magnesium-zinc-calcium-vitamin D group · Women aged 18–40 with gestational diabetes mellitus, at 24–28 weeks’ gestation at diagnosis
200 mg800 mg6 weeks30
Activation of the calcium sensing receptor stimulates gastrin and gastric acid secretion in healthy participants
2009 · cinacalcet group · Healthy men and postmenopausal women aged 45–70 years
100 mg1.2 g11 days9
Activation of the calcium sensing receptor stimulates gastrin and gastric acid secretion in healthy participants
2009 · placebo group · Healthy men and postmenopausal women aged 45–70 years
100 mg1.2 g11 days8
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), premenopausal women · Premenopausal women, mean age 41 years; no specific condition stated
96 mg1 g12 weeks—
Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women
2016 · Intervention (Int), postmenopausal women · Postmenopausal women, mean age 59 years; no specific condition stated
96 mg1.2 g12 weeks—
Magnesium and Calcium: study protocols | supp.fit