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Leucine, Branched-Chain Amino Acids and Isoleucine: study protocols

8 study groups took Leucine together with Branched-Chain Amino Acids and Isoleucine. These are the doses the studies gave. They are not a recommendation.

Leucine: what the research found →

Dose per serving from research: Leucine

8 study groups in 3 studies say how much Leucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 50% of 8 study groups.

Daily doseStudy groups
10 mg to 25 mg
4
25 mg to 50 mg
2
50 mg to 100 mg
0
100 mg to 250 mg
0
250 mg to 500 mg
0
500 mg to 1 g
0
1 g to 2.5 g
0
2.5 g to 5 g
2

Dose per serving from research: Branched-Chain Amino Acids

6 study groups in 1 study say how much Branched-Chain Amino Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg/kg to 25 mg/kg, 67% of 6 study groups.

Daily doseStudy groups
10 mg/kg to 25 mg/kg
4
25 mg/kg to 50 mg/kg
0
50 mg/kg to 100 mg/kg
2

Dose per serving from research: Isoleucine

6 study groups in 1 study say how much Isoleucine participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg/kg to 100 mg/kg, 67% of 6 study groups.

Daily doseStudy groups
10 mg/kg to 25 mg/kg
2
25 mg/kg to 50 mg/kg
0
50 mg/kg to 100 mg/kg
4

Commonly used together

1 of 8 study groups took Leucine, Branched-Chain Amino Acids and Isoleucine with something else, but nothing that 3 or more different studies gave.

8 study groups

Study
Post-exercise branched chain amino acid supplementation does not affect recovery markers following three consecutive high intensity resistance training bouts compared to carbohydrate supplementation
2016 · BCAA-CHO · Resistance-trained, apparently healthy males; mean age 21.8 years
3 g—1 g4 days15
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 40 mg/kg/day, valine 80 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
40 mg80 mg/kg62 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 15 mg/kg/day, valine 80 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
15 mg80 mg/kg62 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 1: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; six subjects were in phase 1
15 mg20 mg/kg62 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 62 mg/kg/day · Healthy young adult men; five subjects were in phase 2
15 mg20 mg/kg62 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 40 mg/kg/day, valine 20 mg/kg/day, isoleucine 20 mg/kg/day · Healthy young adult men; five subjects were in phase 2
40 mg20 mg/kg20 mg/kg5 days—
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes
1991 · Phase 2: leucine 15 mg/kg/day, valine 20 mg/kg/day, isoleucine 20 mg/kg/day · Healthy young adult men; five subjects were in phase 2
15 mg20 mg/kg20 mg/kg5 days—
Dileucine-supplemented essential amino acids support whole-body anabolism after resistance exercise and serum-stimulated cell-based anabolism
2025 · Branched-chain amino acid (BCAA) supplement · Healthy recreationally active adults, 27.0 ± 4.7 years old; 8 men and 4 women
3.1 g1.5 g1.5 g1 day12
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