Iron and Vitamin C: study protocols
34 study groups took Iron together with Vitamin C. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Iron
34 study groups in 25 studies say how much Iron participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 35% of 34 study groups.
| Daily dose | Study groups |
|---|---|
| 2.5 mg to 5 mg | 3 |
| 5 mg to 10 mg | 11 |
| 10 mg to 25 mg | 4 |
| 25 mg to 50 mg | 12 |
| 50 mg to 100 mg | 4 |
Dose per serving from research: Vitamin C
29 study groups in 22 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg and 50 mg to 100 mg, 34% of 29 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 2 |
| 25 mg to 50 mg | 10 |
| 50 mg to 100 mg | 10 |
| 100 mg to 250 mg | 3 |
Commonly used together
29 of 34 study groups took Iron and Vitamin C with something else. Shown: what 3 or more different studies gave. The 10 most common of 15.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin A | 26 |
| Folic Acid | 23 |
| Zinc | 22 |
| Copper | 16 |
| Vitamin E | 16 |
| Iodine | 14 |
| Vitamin D | 14 |
| Selenium | 13 |
| Vitamin B12 | 13 |
| Niacin | 12 |
34 study groups
| Study | ||||
|---|---|---|---|---|
| Impact of micronutrient supplementation during pregnancy on birth weight, duration of gestation, and perinatal mortality in rural western China: double blind cluster randomised controlled trial 2008 · Multiple micronutrients · Pregnant women resident in disadvantaged rural counties in Shaanxi Province, China; eligible women enrolled before 28 weeks’ gestation | 30 mg | 70 mg | — | 1,899 |
| Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh 2014 · EMMS (early food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation | 30 mg | 70 mg | — | — |
| Equity in adherence to and effect of prenatal food and micronutrient supplementation on child mortality: results from the MINIMat randomized trial, Bangladesh 2014 · UMMS (usual food invitation; multiple micronutrients) · Pregnant women in rural Bangladesh, enrolled before 14 weeks’ gestation | 30 mg | 70 mg | — | — |
| Modifying effects of maternal Hb concentration on infant birth weight in women receiving prenatal iron-containing supplements: a randomised controlled trial 2016 · MMN group · Pregnant women aged at least 20 years, nulliparous, with Hb concentration ≥100 g/L and enrolled before 20 weeks of gestation | 30 mg | 70 mg | — | — |
| Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods 2001 · sprinkles group · Anemic children aged 6–18 months in rural Ghana | 80 mg | — | 60 days | — |
| Impact of iron fortification on anaemia and iron deficiency among pre-school children living in Rural Ghana 2021 · iron-MNP group · Children aged 6–35 months living in rural Ghana; children with severe anaemia, severe malnutrition, recent iron supplementation, or chronic disease were excluded. | 12.5 mg | 30 mg | 150 days | 967 |
| Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa 2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers | 10 mg | 35 mg | 548 days | — |
| Predictors of adherence to micronutrient supplementation before and during pregnancy in Vietnam 2017 · MM (multiple micronutrients) preconception group · Women of reproductive age in Vietnam intending to become pregnant | 8.57 mg | 10 mg | 54 weeks | 1,469 |
| Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia 2025 · MMS-180 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy | 30 mg | 70 mg | 180 days | 516 |
| Assessing the adherence and acceptability to iron and folic acid compared with multiple micronutrient supplements during pregnancy: a cluster-randomized noninferiority trial in Cambodia 2025 · MMS-90 · Healthy pregnant individuals aged 18–45 years, in the first 14 weeks of a low-risk singleton pregnancy | 30 mg | 70 mg | 180 days | 515 |