supp.fit

HMB and Vitamin D: study protocols

7 study groups took HMB together with Vitamin D. These are the doses the studies gave. They are not a recommendation.

HMB: what the research found →

Dose per serving from research: HMB

7 study groups in 5 studies say how much HMB participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 g to 5 g, 86% of 7 study groups.

Daily doseStudy groups
1 g to 2.5 g
1
2.5 g to 5 g
6

Dose per serving from research: Vitamin D

6 study groups in 4 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1,000 IU to 2,500 IU, 67% of 6 study groups.

Daily doseStudy groups
500 IU to 1,000 IU
2
1,000 IU to 2,500 IU
4

Commonly used together

2 of 7 study groups took HMB and Vitamin D with something else, but nothing that 3 or more different studies gave.

7 study groups

Study
A Novel Fortified Dairy Product and Sarcopenia Measures in Sarcopenic Older Adults: A Double-Blind Randomized Controlled Trial
2021 · intervention group · Community-recruited older adults with sarcopenia
3 g1,000 IU12 weeks33
Long-term Effects of Calcium β-Hydroxy-β-Methylbutyrate and Vitamin D3 Supplementation on Muscular Function in Older Adults With and Without Resistance Training: A Randomized, Double-blind, Controlled Study
2020 · HMB+D + exercise · Men and women aged 60 years or older with insufficient, but not clinically deficient, 25-hydroxyvitamin D levels (15–30 ng/mL)
3 g2,000 IU1 year30
Long-term Effects of Calcium β-Hydroxy-β-Methylbutyrate and Vitamin D3 Supplementation on Muscular Function in Older Adults With and Without Resistance Training: A Randomized, Double-blind, Controlled Study
2020 · HMB+D + no exercise · Men and women aged 60 years or older with insufficient, but not clinically deficient, 25-hydroxyvitamin D levels (15–30 ng/mL)
3 g2,000 IU1 year27
Enhanced physical and cognitive performance in active duty Airmen: evidence from a randomized multimodal physical fitness and nutritional intervention
2020 · exercise plus nutritional supplement group · Active-duty Air Force Airmen aged 18–45; no qualifying disease or deficiency was stated
3 g960 IU12 weeks70
Effects of Oral Nutritional Supplement with β-Hydroxy-β-methylbutyrate (HMB) on Biochemical and Hematological Indices in Community-Dwelling Older Adults at Risk of Malnutrition: Findings from the SHIELD Study
2024 · specialized ONS · Community-dwelling men and women aged 65 years or older in Singapore, at medium or high risk of malnutrition
1.48 g15.5 mcg180 days401
Small-Scale Randomized Controlled Trial to Explore the Impact of β-Hydroxy-β-Methylbutyrate Plus Vitamin D(3) on Skeletal Muscle Health in Middle Aged Women
2022 · SED HMB + D · Women aged 45–60 years, apparently healthy, assigned to sedentary control; vitamin D status varied at baseline
3 g2,000 IU12 weeks—
Small-Scale Randomized Controlled Trial to Explore the Impact of β-Hydroxy-β-Methylbutyrate Plus Vitamin D(3) on Skeletal Muscle Health in Middle Aged Women
2022 · RET HMB + D · Women aged 45–60 years, apparently healthy, assigned to resistance exercise training; vitamin D status varied at baseline
3 g2,000 IU12 weeks—
HMB and Vitamin D: study protocols | supp.fit