Cocoa Extract and Multivitamin: study protocols
4 study groups took Cocoa Extract together with Multivitamin. These are the doses the studies gave. They are not a recommendation.
Fewer than 5 study groups in one unit match, too few to draw the chart.
Commonly used together
None of these 4 study groups took Cocoa Extract and Multivitamin with anything else.
4 study groups
| Study | ||||
|---|---|---|---|---|
| Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial 2022 · active cocoa extract and active multivitamin · Women aged 65 years or older and men aged 60 years or older, without recent myocardial infarction, stroke, or cancer (except nonmelanoma skin cancer) | 500 mg | — | 1314 days | — |
| Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial 2023 · Cocoa extract plus multivitamin-mineral (Group 4) · Adults aged 65 years or older from the general population | 500 mg | — | 3 years | — |
| The overlooked impact of background diet and adherence in nutrition trials 2025 · Cocoa extract plus multivitamin intervention · Men aged 60 years or older and women aged 65 years or older in the United States | 500 mg | — | 1314 days | — |
| Effects of 2-year cocoa extract supplementation on inflammaging biomarkers in older US adults: findings from the COcoa Supplement and Multivitamin Outcomes Study randomised clinical trial 2025 · Cocoa extract plus multivitamin group · Women aged 65 years or older and men aged 60 years or older | 500 mg | — | 2 years | — |