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Choline: study protocols

21 study groups say how much Choline participants took a day. These are the doses the studies gave. They are not a recommendation.

Choline: what the research found →

Dose per serving from products

6,503 products in our catalogue print how much Choline a serving holds.

Most common: 10 mg to 25 mg, 22% of 6,503 products.

Dose per servingProducts
25 mcg or less
168
25 mcg to 50 mcg
265
50 mcg to 100 mcg
56
100 mcg to 250 mcg
12
250 mcg to 500 mcg
31
500 mcg to 1 mg
25
1 mg to 2.5 mg
67
2.5 mg to 5 mg
169
5 mg to 10 mg
488
10 mg to 25 mg
1,417
25 mg to 50 mg
1,258
50 mg to 100 mg
1,125
100 mg to 250 mg
766
250 mg to 500 mg
396
over 500 mg
260

Dose per serving from research

21 study groups in 12 studies say how much Choline participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 48% of 21 study groups.

Daily doseStudy groups
100 mg or less
1
100 mg to 250 mg
1
250 mg to 500 mg
6
500 mg to 1 g
10
1 g to 2.5 g
3

Commonly used together

5 of 21 study groups took Choline with something else, but nothing that 3 or more different studies gave.

21 study groups

Study
Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial
2003 · CA group · Adults aged 60–80 with mild to moderate Alzheimer-type dementia
1.2 g180 days132
Maternal choline supplementation during the third trimester of pregnancy improves infant information processing speed: a randomized, double-blind, controlled feeding study
2018 · 480 mg choline/d group · Women entering their third trimester of pregnancy
480 mg—13
Maternal choline supplementation during the third trimester of pregnancy improves infant information processing speed: a randomized, double-blind, controlled feeding study
2018 · 930 mg choline/d group · Women entering their third trimester of pregnancy
930 mg—13
Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes
2021 · choline-treated arm · Pregnant women with heavy alcohol consumption, enrolled before 23 weeks’ gestation; their infants participated in the neonatal imaging study
2 g—28
Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
2018 · choline supplementation arm · Pregnant women aged 18 years or older with heavy prenatal alcohol exposure in Cape Town; infants were assessed as study outcomes.
2.5 g130 days31
Dose and Timing of Prenatal Alcohol Exposure and Maternal Nutritional Supplements: Developmental Effects on 6-Month-Old Infants
2015 · MVM + choline group · Pregnant women, including moderate-to-heavy alcohol drinkers and low/unexposed comparison women; maternal age not specified
750 mg——
Choline, an essential nutrient for humans
1991 · control (continued to receive choline) · Healthy male volunteers; age not reported
500 mg5 weeks—
Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
2012 · 480 mg choline/d, pregnant women · Healthy pregnant women, 27 weeks gestation
480 mg12 weeks—
Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
2012 · 930 mg choline/d, pregnant women · Healthy pregnant women, 27 weeks gestation
930 mg12 weeks—
Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
2012 · 480 mg choline/d, nonpregnant women · Healthy nonpregnant women
480 mg12 weeks—