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Calcium, Vitamin B12, Folic Acid and Vitamin D: study protocols

7 study groups took Calcium together with Vitamin B12, Folic Acid and Vitamin D. These are the doses the studies gave. They are not a recommendation.

Calcium: what the research found →

Dose per serving from research: Calcium

7 study groups in 6 studies say how much Calcium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 57% of 7 study groups.

Daily doseStudy groups
100 mg to 250 mg
1
250 mg to 500 mg
2
500 mg to 1 g
4

Dose per serving from research: Vitamin B12

7 study groups in 6 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 43% of 7 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
2
10 mcg to 25 mcg
0
25 mcg to 50 mcg
0
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
3
500 mcg to 1 mg
2

Dose per serving from research: Folic Acid

7 study groups in 6 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 86% of 7 study groups.

Daily doseStudy groups
250 mcg to 500 mcg
6
500 mcg to 1 mg
1

Commonly used together

7 of 7 study groups took Calcium, Vitamin B12, Folic Acid and Vitamin D with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin B6
5

7 study groups

Study
A smartphone application to improve adherence to vitamin and mineral supplementation after bariatric surgery
2022 · Intervention group · Adults aged over 18 to 60 years undergoing gastric bypass or sleeve gastrectomy
1 g1 mg400 mcg—1 year71
A smartphone application to improve adherence to vitamin and mineral supplementation after bariatric surgery
2022 · Control group · Adults aged over 18 to 60 years undergoing gastric bypass or sleeve gastrectomy
1 g1 mg400 mcg—1 year69
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
150 mg5.2 mcg400 mcg10 mcg—870
Mineral water fortified with folic acid, vitamins B6, B12, D and calcium improves folate status and decreases plasma homocysteine concentration in men and women
2004 · Fortified mineral water · Free-living men and women without folate deficiency or elevated homocysteine
563 mg7.5 mcg563 mcg0.6 mcg8 weeks—
Plasma trimethylamine-N-oxide following supplementation with vitamin D or D plus B vitamins
2017 · vitamin D + B arm · Participants; age, sex, and health condition not specified
800 mg500 mcg500 mcg1,200 IU1 year25
One year B and D vitamins supplementation improves metabolic bone markers
2013 · group A · Healthy adults older than 54 years
456 mg500 mcg500 mcg1,200 IU1 year—
One-carbon metabolites and telomere length in a prospective and randomized study of B- and/or D-vitamin supplementation
2017 · group A · Adults older than 54 years; no specific condition stated
456 mg500 mcg500 mcg1,200 IU1 year—
Calcium, Vitamin B12, Folic Acid and Vitamin D: study protocols | supp.fit