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Alpha-Linolenic Acid and Omega-3 Fatty Acids: study protocols

10 study groups took Alpha-Linolenic Acid together with Omega-3 Fatty Acids. These are the doses the studies gave. They are not a recommendation.

Alpha-Linolenic Acid: what the research found →

Dose per serving from research: Alpha-Linolenic Acid

10 study groups in 10 studies say how much Alpha-Linolenic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 40% of 10 study groups.

Daily doseStudy groups
100 mg to 250 mg
2
250 mg to 500 mg
1
500 mg to 1 g
4
1 g to 2.5 g
2
2.5 g to 5 g
1

Dose per serving from research: Omega-3 Fatty Acids

9 study groups in 9 studies say how much Omega-3 Fatty Acids participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg and 250 mg to 500 mg and 500 mg to 1 g and 1 g to 2.5 g, 22% of 9 study groups each.

Daily doseStudy groups
100 mg to 250 mg
2
250 mg to 500 mg
2
500 mg to 1 g
2
1 g to 2.5 g
2
2.5 g to 5 g
0
5 g to 10 g
0
10 g to 25 g
1

Commonly used together

6 of 10 study groups took Alpha-Linolenic Acid and Omega-3 Fatty Acids with something else, but nothing that 3 or more different studies gave.

10 study groups

Study
n-3 fatty acids, ventricular arrhythmia-related events, and fatal myocardial infarction in postmyocardial infarction patients with diabetes
2011 · EPA-DHA plus ALA · Adults aged 60–80 with diabetes and a previous myocardial infarction
2 g400 mg1217 days245
Effects of n-3 fatty acids on major cardiovascular events in statin users and non-users with a history of myocardial infarction
2012 · EPA-DHA plus ALA · Adults with a history of myocardial infarction; statin users and non-users
2 g400 mg——
Consumption of echium oil increases EPA and DPA in blood fractions more efficiently compared to linseed oil in humans
2016 · Echium oil (EO) · Adults aged 20–69 years, women and men, including normal-weight and overweight participants; no chronic disease reported
5 g17 g8 weeks60
Bioavailability of Dietary Omega-3 Fatty Acids Added to a Variety of Sausages in Healthy Individuals
2017 · verum group · Healthy adults aged 20–60 years with Omega-3 Index below 5%
240 mg250 mg8 weeks22
Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials
2017 · small-quantity lipid-based nutrient supplement (SQ-LNS) · Pregnant women in Ghana and Malawi; Ghana participants were at least 18 years old, and Malawi participants were at least 15 years old
590 mg—56 weeks—
The Effects of Omega-3 Fatty Acids and Vitamin E Co-Supplementation on Indices of Insulin Resistance and Hormonal Parameters in Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
2017 · omega-3 fatty acids and vitamin E co-supplementation · Women aged 18–40 years with polycystic ovary syndrome
400 mg1 g12 weeks34
The Effects of Omega-3 Fatty Acids Supplementation on Gene Expression Involved in the Insulin and Lipid Signaling Pathway in Patients with Polycystic Ovary Syndrome
2017 · omega-3 fatty acids from flaxseed oil · Women aged 18–40 diagnosed with polycystic ovary syndrome according to the Rotterdam criteria
800 mg2 g12 weeks30
The effects of n-3 fatty acids from flaxseed oil on genetic and metabolic profiles in patients with gestational diabetes mellitus: a randomised, double-blind, placebo-controlled trial
2020 · n-3 fatty acids from flaxseed oil · Women with gestational diabetes mellitus
800 mg2 g6 weeks30
Influence of low-dose polyunsaturated fatty acids supplementation on the inflammatory response of healthy adults
2007 · group A (anti-inflammatory blend) · healthy adult volunteers
240 mg169 mg2 weeks—
Use of a Micronutrient Cocktail to Improve Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Adults with Obesity: A Randomized, Double-Blinded Pilot Clinical Trial
2024 · intervention group · Adults aged 18–70 with obesity and dyslipidemia
1 g700 mg90 days105
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