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Alpha-Linolenic Acid and Flaxseed Oil: study protocols

8 study groups took Alpha-Linolenic Acid together with Flaxseed Oil. These are the doses the studies gave. They are not a recommendation.

Alpha-Linolenic Acid: what the research found →

Dose per serving from research: Alpha-Linolenic Acid

8 study groups in 8 studies say how much Alpha-Linolenic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 38% of 8 study groups.

Daily doseStudy groups
500 mg to 1 g
3
1 g to 2.5 g
1
2.5 g to 5 g
2
5 g to 10 g
1
10 g to 25 g
1

Dose per serving from research: Flaxseed Oil

6 study groups in 6 studies say how much Flaxseed Oil participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 g to 25 g, 50% of 6 study groups.

Daily doseStudy groups
2.5 g or less
1
2.5 g to 5 g
1
5 g to 10 g
1
10 g to 25 g
3

Commonly used together

1 of 8 study groups took Alpha-Linolenic Acid and Flaxseed Oil with something else, but nothing that 3 or more different studies gave.

8 study groups

Study
Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults
2023 · ALA group · Healthy right-handed men and women aged 65–80 years without cognitive impairment
2.2 g3.7 g12 weeks30
Effects of diacylglycerol-enriched alpha-linolenic acid oil on skin properties in mild skin discomfort: a randomized, double-blind, placebo-controlled study
2026 · ALA-DAG group · Men and women aged 20–59 with mild subjective skin discomfort and occasional allergy-like symptoms, without a clinical diagnosis of allergic disease
900 mg2.5 g8 weeks30
Effect of α-linolenic acid on vascular function and metabolic risk markers during the fasting and postprandial phase: A randomized placebo-controlled trial in untreated (pre-)hypertensive individuals
2020 · Flaxseed oil · Overweight and obese adults aged 60 ± 8 years with high-normal blood pressure or mild (stage I) hypertension
4.7 g10 g12 weeks29
Consumption of echium oil increases EPA and DPA in blood fractions more efficiently compared to linseed oil in humans
2016 · Linseed oil mixture (LO) · Adults aged 20–69 years, women and men, including normal-weight and overweight participants; no chronic disease reported
5 g17 g8 weeks60
Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition
2013 · FXCO diet · Hyperlipidemic subjects; age and sex not specified
20.6 g20.6 g4 weeks36
The Effects of Omega-3 Fatty Acids Supplementation on Gene Expression Involved in the Insulin and Lipid Signaling Pathway in Patients with Polycystic Ovary Syndrome
2017 · omega-3 fatty acids from flaxseed oil · Women aged 18–40 diagnosed with polycystic ovary syndrome according to the Rotterdam criteria
800 mg—12 weeks30
Flaxseed Oil Supplementation Improve Gene Expression Levels of PPAR-γ, LP(a), IL-1 and TNF-α in Type 2 Diabetic Patients with Coronary Heart Disease
2017 · Flaxseed oil group · Overweight adults with type 2 diabetes and coronary heart disease; sex and age range not reported
800 mg—12 weeks30
Dietary milled flaxseed and flaxseed oil improve N-3 fatty acid status and do not affect glycemic control in individuals with well-controlled type 2 diabetes
2010 · flaxseed oil (FXO) · Adults with well-controlled type 2 diabetes; mean age 52.4 years; men and women
7.4 g13 g12 weeks12
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