Zinc, Vitamin E, Vitamin C, Vitamin D and Niacin: study protocols
6 study groups took Zinc together with Vitamin E, Vitamin C, Vitamin D and Niacin. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Zinc
6 study groups in 5 studies say how much Zinc participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg and 25 mg to 50 mg, 50% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 3 |
Dose per serving from research: Vitamin E
5 study groups in 4 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg, 60% of 5 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 3 |
| 10 mg to 25 mg | 2 |
Dose per serving from research: Vitamin C
5 study groups in 4 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg and 100 mg to 250 mg, 40% of 5 study groups each.
| Daily dose | Study groups |
|---|---|
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 1 |
| 100 mg to 250 mg | 2 |
Dose per serving from research: Niacin
5 study groups in 4 studies say how much Niacin participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg and 25 mg to 50 mg, 40% of 5 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 1 |
| 25 mg to 50 mg | 2 |
Commonly used together
6 of 6 study groups took Zinc, Vitamin E, Vitamin C, Vitamin D and Niacin with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Copper | 6 |
| Iron | 6 |
| Vitamin A | 6 |
| Iodine | 5 |
| Vitamin B12 | 4 |
| Vitamin B6 | 4 |
| Vitamin K | 4 |
| folate | 3 |
| vitamin B1 | 3 |
| vitamin B2 | 3 |
6 study groups
| Study | |||||||
|---|---|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 30 mg | 10 mg | 100 mg | 10 mcg | 20 mg | — | — |
| Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa 2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers | 10 mg | 6 mg | 35 mg | 5 mcg | 6 mg | 548 days | — |
| Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial 2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania | 10 mg | — | — | — | — | — | 151 |
| Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months 2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes | 10 mg | 6 mg | 35 mg | 5 mcg | 6 mg | 548 days | 126 |
| mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status 2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia | 30 mg | 20 mg | 140 mg | 400 IU | 36 mg | 184 days | 75 |
| mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status 2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia | 30 mg | 20 mg | 140 mg | 400 IU | 36 mg | 184 days | 75 |