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Zinc, Vitamin E, Selenium, Copper and Folic Acid: study protocols

5 study groups took Zinc together with Vitamin E, Selenium, Copper and Folic Acid. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

5 study groups in 4 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg and 25 mg to 50 mg, 40% of 5 study groups each.

Daily doseStudy groups
10 mg or less
1
10 mg to 25 mg
2
25 mg to 50 mg
2

Dose per serving from research: Vitamin E

5 study groups in 4 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 80% of 5 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
0
10 mg to 25 mg
4

Dose per serving from research: Selenium

5 study groups in 4 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mcg to 100 mcg and 100 mcg to 250 mcg, 40% of 5 study groups each.

Daily doseStudy groups
25 mcg or less
1
25 mcg to 50 mcg
0
50 mcg to 100 mcg
2
100 mcg to 250 mcg
2

Dose per serving from research: Copper

5 study groups in 4 studies say how much Copper participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 60% of 5 study groups.

Daily doseStudy groups
500 mcg to 1 mg
3
1 mg to 2.5 mg
0
2.5 mg to 5 mg
2

Dose per serving from research: Folic Acid

5 study groups in 4 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg and 500 mcg to 1 mg, 40% of 5 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
1
250 mcg to 500 mcg
2
500 mcg to 1 mg
2

Commonly used together

5 of 5 study groups took Zinc, Vitamin E, Selenium, Copper and Folic Acid with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iodine
5
Iron
5
Vitamin A
5
Vitamin C
5
Vitamin D
4
Vitamin B12
3

5 study groups

Study
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg15 mg60 mcg1 mg600 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg15 mg60 mcg1 mg600 mcg—176
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg20 mg130 mcg4 mg400 mcg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg20 mg130 mcg4 mg400 mcg184 days75
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg5 mg17 mcg560 mcg150 mcg22 weeks175