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Zinc, Vitamin D, Copper, Vitamin E and Selenium: study protocols

7 study groups took Zinc together with Vitamin D, Copper, Vitamin E and Selenium. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

7 study groups in 6 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 43% of 7 study groups.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
3
25 mg to 50 mg
2

Dose per serving from research: Copper

6 study groups in 5 studies say how much Copper participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg and 2.5 mg to 5 mg, 33% of 6 study groups each.

Daily doseStudy groups
500 mcg or less
1
500 mcg to 1 mg
2
1 mg to 2.5 mg
1
2.5 mg to 5 mg
2

Dose per serving from research: Vitamin E

6 study groups in 5 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 67% of 6 study groups.

Daily doseStudy groups
5 mg to 10 mg
1
10 mg to 25 mg
4
25 mg to 50 mg
1

Dose per serving from research: Selenium

7 study groups in 6 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mcg to 25 mcg and 50 mcg to 100 mcg and 100 mcg to 250 mcg, 29% of 7 study groups each.

Daily doseStudy groups
10 mcg to 25 mcg
2
25 mcg to 50 mcg
1
50 mcg to 100 mcg
2
100 mcg to 250 mcg
2

Commonly used together

7 of 7 study groups took Zinc, Vitamin D, Copper, Vitamin E and Selenium with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
7
Vitamin C
7
Iodine
6
Vitamin A
6
Folic Acid
5
Niacin
5
Vitamin B12
5
Vitamin B6
4

7 study groups

Study
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
20 mg5 mcg2 mg8 mg40 mcg335 days—
Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial
2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania
10 mg—340 mcg—20 mcg—151
Effects of Low-Dose Dairy Protein Plus Micronutrient Supplementation during Resistance Exercise on Muscle Mass and Physical Performance in Older Adults: A Randomized, Controlled Trial
2018 · ExPM (resistance exercise plus low-dose dairy protein and micronutrient supplementation) · Adults aged 65–80 years, non-disabled and not exercising regularly
8 mg5 mcg—30 mg25 mcg12 weeks40
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg5 mcg1 mg15 mg60 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg5 mcg1 mg15 mg60 mcg—176
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg400 IU4 mg20 mg130 mcg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg400 IU4 mg20 mg130 mcg184 days75
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