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Zinc, Vitamin C, Folic Acid, Vitamin E and Copper: study protocols

6 study groups took Zinc together with Vitamin C, Folic Acid, Vitamin E and Copper. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

6 study groups in 5 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 50% of 6 study groups.

Daily doseStudy groups
10 mg or less
1
10 mg to 25 mg
2
25 mg to 50 mg
3

Dose per serving from research: Vitamin C

6 study groups in 5 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 50% of 6 study groups.

Daily doseStudy groups
25 mg to 50 mg
1
50 mg to 100 mg
3
100 mg to 250 mg
2

Dose per serving from research: Folic Acid

6 study groups in 5 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 50% of 6 study groups.

Daily doseStudy groups
100 mcg to 250 mcg
1
250 mcg to 500 mcg
3
500 mcg to 1 mg
2

Dose per serving from research: Vitamin E

6 study groups in 5 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 67% of 6 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
1
10 mg to 25 mg
4

Dose per serving from research: Copper

6 study groups in 5 studies say how much Copper participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg, 50% of 6 study groups.

Daily doseStudy groups
500 mcg to 1 mg
3
1 mg to 2.5 mg
1
2.5 mg to 5 mg
2

Commonly used together

6 of 6 study groups took Zinc, Vitamin C, Folic Acid, Vitamin E and Copper with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
6
Vitamin A
6
Iodine
5
Selenium
5
Vitamin D
5
Vitamin B12
4
Vitamin B6
3

6 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg100 mg400 mcg10 mg2 mg——
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg85 mg600 mcg15 mg1 mg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg85 mg600 mcg15 mg1 mg—176
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg140 mg400 mcg20 mg4 mg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg140 mg400 mcg20 mg4 mg184 days75
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg30 mg150 mcg5 mg560 mcg22 weeks175