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Zinc, Vitamin C, Beta-Carotene and Copper: study protocols

5 study groups took Zinc together with Vitamin C, Beta-Carotene and Copper. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

5 study groups in 3 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg, 80% of 5 study groups.

Daily doseStudy groups
25 mg or less
1
25 mg to 50 mg
0
50 mg to 100 mg
4

Dose per serving from research: Vitamin C

5 study groups in 3 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mg to 500 mg, 100% of 5 study groups.

Daily doseStudy groups
250 mg to 500 mg
5

Dose per serving from research: Beta-Carotene

5 study groups in 3 studies say how much Beta-Carotene participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 100% of 5 study groups.

Daily doseStudy groups
10 mg to 25 mg
5

Commonly used together

5 of 5 study groups took Zinc, Vitamin C, Beta-Carotene and Copper with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin E
5

5 study groups

Study
Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis
2016 · combination of antioxidants and zinc · Adults aged 55 years and older with age-related macular degeneration; eyes with advanced disease at baseline and participants with no AMD in both eyes were excluded
80 mg500 mg15 mg2 mg2409 days—
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
80 mg500 mg15 mg2 mg8 years—
Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration
2025 · AREDS antioxidants plus zinc · Adults aged 55–80 with early or more advanced age-related macular degeneration
80 mg500 mg15 mg2 mg5 years—
Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration
2025 · AREDS2 original AREDS formulation · Adults aged 50–85 with large drusen in both eyes or late AMD in one eye and large drusen in the fellow eye who accepted the additional AREDS formulation
80 mg500 mg15 mg2 mg5 years—
Oral Antioxidant and Lutein/Zeaxanthin Supplements Slow Geographic Atrophy Progression to the Fovea in Age-Related Macular Degeneration
2025 · AREDS2 original AREDS formulation with low zinc · Adults aged 50–85 with large drusen in both eyes or late AMD in one eye and large drusen in the fellow eye who accepted the additional AREDS formulation
25 mg500 mg15 mg—5 years—