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Zinc, Vitamin A, Vitamin E, Selenium and Vitamin C: study protocols

7 study groups took Zinc together with Vitamin A, Vitamin E, Selenium and Vitamin C. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

7 study groups in 6 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 43% of 7 study groups.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
2
25 mg to 50 mg
2

Dose per serving from research: Vitamin A

6 study groups in 5 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mcg to 1 mg and 1 mg to 2.5 mg, 33% of 6 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
1
250 mcg to 500 mcg
1
500 mcg to 1 mg
2
1 mg to 2.5 mg
2

Dose per serving from research: Vitamin E

6 study groups in 5 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 67% of 6 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
1
10 mg to 25 mg
4

Dose per serving from research: Selenium

7 study groups in 6 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mcg to 25 mcg and 50 mcg to 100 mcg and 100 mcg to 250 mcg, 29% of 7 study groups each.

Daily doseStudy groups
5 mcg or less
1
5 mcg to 10 mcg
0
10 mcg to 25 mcg
2
25 mcg to 50 mcg
0
50 mcg to 100 mcg
2
100 mcg to 250 mcg
2

Dose per serving from research: Vitamin C

6 study groups in 5 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg and 50 mg to 100 mg and 100 mg to 250 mg, 33% of 6 study groups each.

Daily doseStudy groups
25 mg to 50 mg
2
50 mg to 100 mg
2
100 mg to 250 mg
2

Commonly used together

7 of 7 study groups took Zinc, Vitamin A, Vitamin E, Selenium and Vitamin C with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Copper
7
Iron
7
Iodine
6
Folic Acid
5
Vitamin D
5
Vitamin B12
4
Vitamin B6
3

7 study groups

Study
Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial
2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania
10 mg——20 mcg——151
Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial
2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering
7.8 mg156 mcg7.5 mg4.2 mcg40.2 mg1 year316
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg770 mcg15 mg60 mcg85 mg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg770 mcg15 mg60 mcg85 mg—176
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg1.6 mg20 mg130 mcg140 mg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg1.6 mg20 mg130 mcg140 mg184 days75
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg400 mcg5 mg17 mcg30 mg22 weeks175