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Zinc, Vitamin A, Folic Acid and Vitamin C: study protocols

9 study groups took Zinc together with Vitamin A, Folic Acid and Vitamin C. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

9 study groups in 8 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 33% of 9 study groups.

Daily doseStudy groups
2.5 mg to 5 mg
2
5 mg to 10 mg
2
10 mg to 25 mg
2
25 mg to 50 mg
3

Dose per serving from research: Vitamin A

8 study groups in 7 studies say how much Vitamin A participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg and 500 mcg to 1 mg, 38% of 8 study groups each.

Daily doseStudy groups
250 mcg to 500 mcg
3
500 mcg to 1 mg
3
1 mg to 2.5 mg
2

Dose per serving from research: Folic Acid

8 study groups in 7 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg and 250 mcg to 500 mcg, 38% of 8 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
3
250 mcg to 500 mcg
3
500 mcg to 1 mg
2

Dose per serving from research: Vitamin C

8 study groups in 7 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg and 50 mg to 100 mg, 38% of 8 study groups each.

Daily doseStudy groups
25 mg to 50 mg
3
50 mg to 100 mg
3
100 mg to 250 mg
2

Commonly used together

9 of 9 study groups took Zinc, Vitamin A, Folic Acid and Vitamin C with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
9
Copper
6
Vitamin D
6
Vitamin E
6
Iodine
5
Selenium
5
Vitamin B12
4
Vitamin B6
3

9 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg1 mg400 mcg100 mg——
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg770 mcg600 mcg85 mg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
12 mg770 mcg600 mcg85 mg—176
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg1.6 mg400 mcg140 mg184 days75
mRNA Levels of Placental Iron and Zinc Transporter Genes Are Upregulated in Gambian Women with Low Iron and Zinc Status
2017 · PE+MMN group · Pregnant women aged 18–45 years with singleton pregnancies under 20 weeks in rural Gambia
30 mg1.6 mg400 mcg140 mg184 days75
Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: a cluster-randomised trial
2006 · daily group · Children aged 3–6 years in a kindergarten in northern China
5 mg300 mcg150 mcg50 mg13 weeks—
Micronutrient supplements can promote disruptive protozoan and fungal communities in the developing infant gut
2021 · MNP with zinc · Children enrolled at 6 months of age in Pakistan; included undernourished and reference weight-for-length groups
10 mg———1 year889
Micronutrient Sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural Haiti
2007 · Sprinkles-WSB (S-WSB) · Children aged 9–24 months in rural Haiti receiving take-home fortified wheat-soy blend rations
5 mg400 mcg160 mcg30 mg60 days254
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg400 mcg150 mcg30 mg22 weeks175