| The effect of zinc supplementation on pregnancy outcomes: a double-blind, randomised controlled trial, Egypt 2015 · combined group · Pregnant women aged 20–45 years with low serum zinc for gestational age | 30 mg | — | — | 227 |
| Impact of zinc supplementation on persistent diarrhoea in malnourished Bangladeshi children 1998 · Zinc with multivitamin · Children aged 3–24 months with persistent diarrhoea; malnourished children were the focus of the reported benefit | 20 mg | — | 2 weeks | — |
| Megadose vitamins in bladder cancer: a double-blind clinical trial 1994 · megadose vitamins arm · Patients with biopsy-confirmed transitional cell carcinoma of the bladder receiving BCG immunotherapy | 90 mg | — | — | 35 |
| Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania 2005 · Zinc group · Pregnant women with HIV-1 infection, recruited at 12–27 weeks of gestation | 25 mg | — | — | — |
| Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea--a community-based, double-blind, controlled trial 1997 · zinc group · Children aged 6–35 months in a low-socioeconomic-status urban Indian community | 10 mg | — | 26 weeks | 286 |
| Randomized controlled trial of the effect of daily supplementation with zinc or multiple micronutrients on the morbidity, growth, and micronutrient status of young Peruvian children 2004 · Zn+VM · Children aged 6–35 months with persistent diarrhea, supplemented after the diarrhea episode ended | 10 mg | — | 26 weeks | 82 |
| Impact of zinc supplementation on subsequent morbidity and growth in Bangladeshi children with persistent diarrhoea 2007 · Zinc group · Children aged 3–24 months, both sexes, hospitalized with persistent diarrhoea; included malnourished children | 20 mg | — | 2 weeks | 78 |
| Effect of oral zinc supplementation on the growth of preterm infants 2010 · Group I · Preterm infants weighing 1000 to 2500 g | 2 mg/kg | — | 6 weeks | 50 |
| A randomized controlled clinical trial of zinc, vitamin A or both in undernourished children with persistent diarrhea in Bangladesh 2001 · zinc · Bangladeshi children aged 6 months to 2 years with persistent diarrhea and moderate malnutrition | 40 mg | — | 7 days | 24 |
| A randomized controlled clinical trial of zinc, vitamin A or both in undernourished children with persistent diarrhea in Bangladesh 2001 · zinc plus vitamin A · Bangladeshi children aged 6 months to 2 years with persistent diarrhea and moderate malnutrition | 40 mg | — | 7 days | 24 |
| Effect of zinc supplementation on mood states in young women: a pilot study 2010 · MV and Zn group · Young women; age range and health status not specified | 7 mg | — | 10 weeks | 15 |
| Impact of zinc supplementation on subsequent growth and morbidity in Bangladeshi children with acute diarrhoea 1999 · Elemental zinc in multivitamin syrup · Children aged 3–24 months with malnutrition and acute diarrhoea | 20 mg | — | 2 weeks | — |
| Zinc supplementation in the management of shigellosis in malnourished children in Bangladesh 2008 · Zinc (intervention) · Moderately malnourished children aged 12–59 months with culture-proven shigellosis | 20 mg | — | 2 weeks | — |
| Randomised controlled trial of zinc supplementation in malnourished Bangladeshi children with acute diarrhoea 1997 · Zinc-containing multivitamins · Children aged 3 to 24 months with acute diarrhoea and malnutrition (below 76% median weight for age) | 20 mg | — | 2 weeks | — |
| Melatonin, vitamins and minerals supplements for the treatment of Covid-19 and Covid-like illness: A prospective, randomized, double-blind multicenter study 2024 · Treatment group · Adults younger than 60 years with COVID-19 or COVID-like illness, no previous medical history, and not hospitalized | 25 mg | — | — | 82 |
| Effect of zinc plus multivitamin supplementation on growth in school children 2016 · Chelated zinc plus multivitamins · Healthy Thai schoolchildren aged 4–13 years | 20 mg | — | 26 weeks | 70 |
| The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial 2020 · Redoxon® Vita Immune (MVM) · Healthy men and women aged 55–75 years | 10 mg | — | 12 weeks | 21 |
| School-based calcium-vitamin D with micronutrient supplementation enhances bone mass in underprivileged Indian premenarchal girls 2012 · Ca+MZ-group · Premenarchal girls aged 8–12 years from low-income groups in Pune, India | 15 mg | — | 1 year | — |
| Effect of micronutrient supplementation on height velocity of underprivileged girls in comparison with un-supplemented healthy controls 2014 · Ca+MZn+D group (C1) · Underprivileged premenarchal girls aged 8–12 years | 15 mg | — | 1 year | — |
| Effect of zinc added to multi-vitamin supplementation containing low-dose vitamin A on plasma retinol level in children--a double-blind randomized, controlled trial 2007 · Vitamin A with zinc group · Children aged 5–36 months, including children with varied nutritional status | 10 mg | 5 mL | 120 days | 90 |
| Plasma zinc concentration responds to short-term zinc supplementation, but not zinc fortification, in young children in Senegal1,2 2011 · ZnSuppl group · Children aged 9–17 months in Senegal | 6 mg | 6 mg | 15 days | — |
| Plasma zinc concentration responds to short-term zinc supplementation, but not zinc fortification, in young children in Senegal1,2 2011 · ZnFort group · Children aged 9–17 months in Senegal | 6 mg | — | 15 days | — |
| Effects of Multivitamin, Multimineral and Phytonutrient Supplementation on Nutrient Status and Biomarkers of Heart Health Risk in a Russian Population: A Randomized, Double Blind, Placebo Controlled Study 2018 · VMP (Nutrilite Double X™) · Generally healthy adults aged 40–70 years in Moscow with low habitual recommended-food intake (recommended food score <12), predominantly women; no chronic diseases | 6 mg | — | 8 weeks | 60 |
| Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis 2004 · zinc group · Children aged 12–59 months with Shigella infection, acute shigellosis, and moderate malnutrition | 20 mg | — | 2 weeks | 28 |
| Effects of zinc supplementation as adjunct therapy on the systemic immune responses in shigellosis 2005 · zinc group · Children aged 12–59 months with Shigella flexneri infection and mild to moderate malnutrition | 20 mg | — | 2 weeks | 28 |
| Plasma zinc concentration increases within 2 weeks in healthy Senegalese men given liquid supplemental zinc, but not zinc-fortified wheat bread 2011 · zinc supplement · Healthy Senegalese men aged 18 years or older | 15 mg | — | 4 weeks | — |
| Plasma zinc concentration increases within 2 weeks in healthy Senegalese men given liquid supplemental zinc, but not zinc-fortified wheat bread 2011 · moderate zinc fortification · Healthy Senegalese men aged 18 years or older | 7.5 mg | — | 4 weeks | — |
| Plasma zinc concentration increases within 2 weeks in healthy Senegalese men given liquid supplemental zinc, but not zinc-fortified wheat bread 2011 · high zinc fortification · Healthy Senegalese men aged 18 years or older | 15 mg | — | 4 weeks | — |