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Zinc, Folic Acid, Vitamin B12 and Iron: study protocols

5 study groups took Zinc together with Folic Acid, Vitamin B12 and Iron. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

5 study groups in 5 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 40% of 5 study groups.

Daily doseStudy groups
5 mg or less
1
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
1

Dose per serving from research: Folic Acid

5 study groups in 5 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mcg to 250 mcg and 250 mcg to 500 mcg, 40% of 5 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
2
250 mcg to 500 mcg
2
500 mcg to 1 mg
1

Dose per serving from research: Vitamin B12

5 study groups in 5 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 40% of 5 study groups.

Daily doseStudy groups
0.5 mcg to 1 mcg
1
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
2
over 5 mcg
1

Commonly used together

5 of 5 study groups took Zinc, Folic Acid, Vitamin B12 and Iron with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin A
4
Copper
3
Iodine
3
Vitamin B6
3
Vitamin C
3
Vitamin D
3
Vitamin E
3

5 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
30 mg400 mcg2.6 mcg———
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mg400 mcg5.2 mcg12 mg—870
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
12 mg600 mcg2.6 mcg27 mg165 days749
Community-level micronutrient fortification of school lunch meals improved vitamin A, folate, and iron status of schoolchildren in Himalayan villages of India
2010 · multiple micronutrients (treatment group) · Schoolchildren aged 6–10 years in Himalayan villages of India
4.2 mg225 mcg1.35 mcg10 mg240 days—
Multiple micronutrient supplementation improves micronutrient status in primary school children in Hai Phong City, Vietnam: a randomised controlled trial
2021 · intervention · Children aged 6–9 years, apparently healthy, in rural Hai Phong City, Vietnam; included undernourished, normal-weight, and overweight/obese children
10 mg150 mcg0.9 mcg10 mg22 weeks175