Zinc and Copper: study protocols
27 study groups took Zinc together with Copper. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Zinc
27 study groups in 17 studies say how much Zinc participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg, 33% of 27 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 7 |
| 10 mg to 25 mg | 9 |
| 25 mg to 50 mg | 3 |
| 50 mg to 100 mg | 8 |
Dose per serving from research: Copper
24 study groups in 17 studies say how much Copper participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 46% of 24 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mcg to 500 mcg | 6 |
| 500 mcg to 1 mg | 5 |
| 1 mg to 2.5 mg | 11 |
| 2.5 mg to 5 mg | 2 |
Commonly used together
23 of 27 study groups took Zinc and Copper with something else. Shown: what 3 or more different studies gave. The 10 most common of 17.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin C | 17 |
| Vitamin E | 17 |
| Iron | 14 |
| Vitamin A | 10 |
| Selenium | 9 |
| Vitamin D | 9 |
| Iodine | 8 |
| Vitamin B12 | 7 |
| Folic Acid | 6 |
| Niacin | 6 |
27 study groups
| Study | ||||
|---|---|---|---|---|
| A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 2001 · Zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye | 80 mg | 2 mg | 8 years | — |
| Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis 2016 · zinc · Adults aged 55 years and older with age-related macular degeneration; eyes with advanced disease at baseline and participants with no AMD in both eyes were excluded | 80 mg | 2 mg | 2409 days | — |
| Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis 2016 · combination of antioxidants and zinc · Adults aged 55 years and older with age-related macular degeneration; eyes with advanced disease at baseline and participants with no AMD in both eyes were excluded | 80 mg | 2 mg | 2409 days | — |
| A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8 2001 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye | 80 mg | 2 mg | 8 years | — |
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 30 mg | 2 mg | — | — |
| Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa 2009 · multiple micronutrients · children aged 6–24 months; three cohorts: HIV-infected children, HIV-uninfected children born to HIV-infected mothers, and HIV-uninfected children born to HIV-uninfected mothers | 10 mg | 600 mcg | 548 days | — |
| Effect of preventive supplementation with zinc and other micronutrients on non-malarial morbidity in Tanzanian pre-school children: a randomized trial 2012 · Multi-nutrients with zinc · Children aged 6–60 months with height-for-age z-score ≤−1.5 SD, in rural Tanzania | 10 mg | 340 mcg | — | 151 |
| Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial 2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering | 7.8 mg | 270 mcg | 1 year | 316 |
| Effect on longitudinal growth and anemia of zinc or multiple micronutrients added to vitamin A: a randomized controlled trial in children aged 6-24 months 2010 · Multiple micronutrients · Children enrolled at 6 months and followed to 24 months in rural South Africa; HIV-infected and HIV-uninfected children, both sexes | 10 mg | 600 mcg | 548 days | 126 |
| [Vitrum osteomag in prevention of osteoporosis in postmenopausal women: results of the comparative open multicenter trial] 2004 · Group 1: Vitrum Osteomag · Postmenopausal women with osteopenia; age range not reported | 15 mg | 2 mg | 1 year | 125 |