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Zinc and Beta-Carotene: study protocols

16 study groups took Zinc together with Beta-Carotene. These are the doses the studies gave. They are not a recommendation.

Zinc: what the research found →

Dose per serving from research: Zinc

16 study groups in 14 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 50% of 16 study groups.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
8
25 mg to 50 mg
0
50 mg to 100 mg
6

Dose per serving from research: Beta-Carotene

16 study groups in 14 studies say how much Beta-Carotene participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 10 mg to 25 mg, 44% of 16 study groups each.

Daily doseStudy groups
1 mg or less
1
1 mg to 2.5 mg
1
2.5 mg to 5 mg
0
5 mg to 10 mg
7
10 mg to 25 mg
7

Commonly used together

15 of 16 study groups took Zinc and Beta-Carotene with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin C
14
Vitamin E
14
Selenium
7
Copper
5

16 study groups

Study
Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis
2016 · combination of antioxidants and zinc · Adults aged 55 years and older with age-related macular degeneration; eyes with advanced disease at baseline and participants with no AMD in both eyes were excluded
80 mg15 mg2409 days—
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8
2001 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration Categories 2–4 and visual acuity of 20/32 or better in at least one eye
80 mg15 mg8 years—
Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13
2004 · antioxidants plus zinc · Adults aged 55–81 years with AMD categories 2–4 and AREDS ocular eligibility
80 mg15 mg339 weeks—
The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals
2004 · antioxidant supplement group · French women aged 35–60 and men aged 45–60 in the general population
20 mg6 mg2739 days—
Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels?
2005 · daily antioxidant supplementation · French adults: women aged 35–60 years and men aged 45–60 years
20 mg6 mg2739 days—
Antioxidant supplementation increases the risk of skin cancers in women but not in men
2007 · antioxidant group · French adult women and men in a general-population primary-prevention trial
20 mg6 mg2738 days—
Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35
2013 · Antioxidants plus zinc · Adults aged 55–80 with age-related macular degeneration (AREDS categories 1–4)
80 mg15 mg339 weeks—
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mg720 mcg—870
Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: preliminary data of the SU.VI.MAX study
2001 · Antioxidant supplementation group · Women aged 35–60 years and men aged 45–60 years in France, general population
20 mg6 mg2 years—
Effect of 6 month supplementation with different combinations of an association of antioxidant nutrients on biochemical parameters and markers of the antioxidant defence system in the elderly. The Geriatrie/Min.Vit.Aox Network
1996 · VT (vitamins associated with trace elements) · Elderly nursing-home residents aged 65–103 years who were long-term hospitalized
20 mg6 mg26 weeks—