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Zeaxanthin, Vitamin C and Lutein: study protocols

7 study groups took Zeaxanthin together with Vitamin C and Lutein. These are the doses the studies gave. They are not a recommendation.

Zeaxanthin: what the research found →

Dose per serving from research: Zeaxanthin

7 study groups in 6 studies say how much Zeaxanthin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 57% of 7 study groups.

Daily doseStudy groups
500 mcg to 1 mg
2
1 mg to 2.5 mg
4
2.5 mg to 5 mg
1

Dose per serving from research: Lutein

7 study groups in 6 studies say how much Lutein participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg, 71% of 7 study groups.

Daily doseStudy groups
5 mg to 10 mg
5
10 mg to 25 mg
2

Commonly used together

7 of 7 study groups took Zeaxanthin, Vitamin C and Lutein with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Zinc
6
Vitamin E
5
Copper
3

7 study groups

Study
Visual Function and Macular Carotenoid Changes in Eyes with Retinal Drusen-An Open Label Randomized Controlled Trial to Compare a Micronized Lipid-Based Carotenoid Liquid Supplementation and AREDS-2 Formula
2020 · PV group · Adults aged 54–80 with retinal drusen and risk of age-related macular degeneration
2 mg—10 mg26 weeks20
Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year
2008 · treated AMD (T-AMD) group · Patients with nonadvanced age-related macular degeneration; mean age 69.4 years
1 mg180 mg10 mg1 year15
Effects of Macuprev(®) Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up
2019 · AMD-M group · Adults with intermediate age-related macular degeneration; 9 male and 21 female enrolled overall, mean age 69.32 years
4 mg160 mg20 mg26 weeks15
Beneficial Effects of Micronutrient Supplementation in Restoring the Altered Microbiota and Gut-Retina Axis in Patients with Neovascular Age-Related Macular Degeneration-A Randomized Clinical Trial
2024 · intervention group · Adults with neovascular age-related macular degeneration; mean age 77.8 years
2 mg80 mg10 mg26 weeks15
Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study
2013 · D2 (twice daily) · Patients with non-exudative age-related macular degeneration; age and sex not specified
2 mg—20 mg1 year55
Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study
2013 · D1 (once daily) · Patients with non-exudative age-related macular degeneration; age and sex not specified
1 mg—10 mg1 year50
Lutein Complex Supplementation Increases Ocular Blood Flow Biomarkers in Healthy Subjects
2019 · lutein phytochemicals complex · Healthy women, mean age 36.8 ± 12.1 years
2 mg500 mg10 mg3 weeks16
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