Vitamin E, Vitamin C and Selenium: study protocols
13 study groups took Vitamin E together with Vitamin C and Selenium. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin E
13 study groups in 12 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 54% of 13 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 4 |
| 25 mg to 50 mg | 7 |
Dose per serving from research: Vitamin C
13 study groups in 12 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 mg to 250 mg, 54% of 13 study groups.
| Daily dose | Study groups |
|---|---|
| 25 mg to 50 mg | 2 |
| 50 mg to 100 mg | 4 |
| 100 mg to 250 mg | 7 |
Dose per serving from research: Selenium
11 study groups in 10 studies say how much Selenium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mcg to 100 mcg, 82% of 11 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mcg or less | 1 |
| 10 mcg to 25 mcg | 1 |
| 25 mcg to 50 mcg | 0 |
| 50 mcg to 100 mcg | 9 |
Commonly used together
13 of 13 study groups took Vitamin E, Vitamin C and Selenium with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Zinc | 11 |
| Beta-Carotene | 7 |
| Folic Acid | 5 |
| Vitamin B12 | 5 |
| Copper | 4 |
| Iron | 4 |
| Vitamin A | 4 |
| Vitamin B6 | 4 |
| Iodine | 3 |
13 study groups
| Study | |||||
|---|---|---|---|---|---|
| The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals 2004 · antioxidant supplement group · French women aged 35–60 and men aged 45–60 in the general population | 30 mg | 120 mg | 100 mcg | 2739 days | — |
| Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels? 2005 · daily antioxidant supplementation · French adults: women aged 35–60 years and men aged 45–60 years | 30 mg | 120 mg | 100 mcg | 2739 days | — |
| Antioxidant supplementation increases the risk of skin cancers in women but not in men 2007 · antioxidant group · French adult women and men in a general-population primary-prevention trial | 30 mg | 120 mg | — | 2738 days | — |
| Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial 2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering | 7.5 mg | 40.2 mg | 4.2 mcg | 1 year | 316 |
| Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh 2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh | 15 mg | 85 mg | 60 mcg | 165 days | 749 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active group (RCT1, RCT2 and RCT3) · Men and women aged 50 years or older with mild or mild-to-moderate Alzheimer's disease; RCT3 participants were on stable approved Alzheimer's medication, while RCT1 and RCT2 participants were drug-free for Alzheimer's medication. | 40 mg | 80 mg | 60 mcg | 24 weeks | 501 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active product during open-label extension (OLE) · Men and women aged 50 years or older with mild Alzheimer's disease who completed RCT2. | 40 mg | 80 mg | 60 mcg | 24 weeks | 201 |
| Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh 2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified | 15 mg | 85 mg | 60 mcg | — | 176 |
| Multiple Micronutrient Powder Reduces Vitamin E Deficiency in Brazilian Children: A Pragmatic, Controlled Clinical Trial 2019 · intervention group · Children aged 6–9 months at the start of the study, male or female, attending primary health care centers in Goiânia, Brazil | 5 mg | 30 mg | 17 mcg | 90 days | 107 |
| Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: preliminary data of the SU.VI.MAX study 2001 · Antioxidant supplementation group · Women aged 35–60 years and men aged 45–60 years in France, general population | 30 mg | 120 mg | 100 mcg | 2 years | — |