Vitamin E, Vitamin C and Folic Acid: study protocols
6 study groups took Vitamin E together with Vitamin C and Folic Acid. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin E
6 study groups in 5 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 10 mg to 25 mg and 25 mg to 50 mg, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 2 |
| 25 mg to 50 mg | 2 |
Dose per serving from research: Vitamin C
6 study groups in 5 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mg to 100 mg, 83% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 25 mg to 50 mg | 1 |
| 50 mg to 100 mg | 5 |
Dose per serving from research: Folic Acid
6 study groups in 5 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 100 mcg to 250 mcg | 1 |
| 250 mcg to 500 mcg | 3 |
| 500 mcg to 1 mg | 2 |
Commonly used together
6 of 6 study groups took Vitamin E, Vitamin C and Folic Acid with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin B12 | 6 |
| Selenium | 5 |
| Vitamin B6 | 5 |
| Copper | 4 |
| Iron | 4 |
| Vitamin A | 4 |
| Zinc | 4 |
| Iodine | 3 |
| Vitamin D | 3 |
6 study groups
| Study | |||||
|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 10 mg | 100 mg | 400 mcg | — | — |
| Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh 2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh | 15 mg | 85 mg | 600 mcg | 165 days | 749 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active group (RCT1, RCT2 and RCT3) · Men and women aged 50 years or older with mild or mild-to-moderate Alzheimer's disease; RCT3 participants were on stable approved Alzheimer's medication, while RCT1 and RCT2 participants were drug-free for Alzheimer's medication. | 40 mg | 80 mg | 400 mcg | 24 weeks | 501 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active product during open-label extension (OLE) · Men and women aged 50 years or older with mild Alzheimer's disease who completed RCT2. | 40 mg | 80 mg | 400 mcg | 24 weeks | 201 |
| Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh 2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified | 15 mg | 85 mg | 600 mcg | — | 176 |
| Multiple Micronutrient Powder Reduces Vitamin E Deficiency in Brazilian Children: A Pragmatic, Controlled Clinical Trial 2019 · intervention group · Children aged 6–9 months at the start of the study, male or female, attending primary health care centers in Goiânia, Brazil | 5 mg | 30 mg | 150 mcg | 90 days | 107 |