Vitamin E and Selenium: study protocols
21 study groups took Vitamin E together with Selenium. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin E
14 study groups in 13 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 25 mg to 50 mg, 57% of 14 study groups.
| Daily dose | Study groups |
|---|---|
| 5 mg or less | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 4 |
| 25 mg to 50 mg | 8 |
Dose per serving from research: Selenium
19 study groups in 18 studies say how much Selenium participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mcg to 100 mcg, 47% of 19 study groups.
| Daily dose | Study groups |
|---|---|
| 10 mcg or less | 1 |
| 10 mcg to 25 mcg | 2 |
| 25 mcg to 50 mcg | 1 |
| 50 mcg to 100 mcg | 9 |
| 100 mcg to 250 mcg | 6 |
Commonly used together
14 of 21 study groups took Vitamin E and Selenium with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin C | 13 |
| Zinc | 11 |
| Beta-Carotene | 8 |
| Folic Acid | 5 |
| Vitamin B12 | 5 |
| Copper | 4 |
| Iron | 4 |
| Vitamin A | 4 |
| Vitamin B6 | 4 |
| Iodine | 3 |
21 study groups
| Study | ||||
|---|---|---|---|---|
| Selenium and Vitamin E for Prevention of Non-Muscle-Invasive Bladder Cancer Recurrence and Progression: A Randomized Clinical Trial 2023 · selenium and vitamin E · Adults aged 18 years or older with newly diagnosed, pathologically confirmed non-muscle-invasive bladder cancer | 200 IU | 200 mcg | 548 days | 69 |
| Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial 2009 · Factor D · Adults in Linxian, China; age and sex details not given | 30 mg | 50 mcg | 313 weeks | — |
| Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT) 2011 · selenium plus vitamin E group · Healthy men at average risk of prostate cancer; age 50 or older for African Americans and 55 or older for others | 400 IU | 200 mcg | 2008 days | — |
| Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT 2012 · selenium plus vitamin E · Men aged 50 years or older if Black and 55 years or older otherwise, without prior prostate cancer diagnosis | 400 IU | 200 mcg | 6 years | — |
| Plasma tocopherols and risk of prostate cancer in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) 2014 · selenium plus vitamin E · African-American men aged 50 years or older and non-African-American men aged 55 years or older, without specified prostate cancer at enrollment | 400 IU | 200 mcg | — | — |
| The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals 2004 · antioxidant supplement group · French women aged 35–60 and men aged 45–60 in the general population | 30 mg | 100 mcg | 2739 days | — |
| Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels? 2005 · daily antioxidant supplementation · French adults: women aged 35–60 years and men aged 45–60 years | 30 mg | 100 mcg | 2739 days | — |
| Antioxidant supplementation increases the risk of skin cancers in women but not in men 2007 · antioxidant group · French adult women and men in a general-population primary-prevention trial | 30 mg | — | 2738 days | — |
| A randomized controlled trial of vitamin E and selenium on rate of decline in lung function 2015 · Vitamin E and Selenium · Men aged 50 years and older without clinical evidence of prostate cancer | 400 IU | 200 mcg | 5 years | 709 |
| Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial 2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering | 7.5 mg | 4.2 mcg | 1 year | 316 |