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Vitamin D, Zinc and Vitamin B12: study protocols

9 study groups took Vitamin D together with Zinc and Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Vitamin D: what the research found →

Dose per serving from research: Vitamin D

6 study groups in 6 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 67% of 6 study groups.

Daily doseStudy groups
2.5 mcg to 5 mcg
4
5 mcg to 10 mcg
2

Dose per serving from research: Zinc

9 study groups in 9 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 56% of 9 study groups.

Daily doseStudy groups
5 mg to 10 mg
2
10 mg to 25 mg
5
25 mg to 50 mg
2

Dose per serving from research: Vitamin B12

9 study groups in 9 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 2.5 mcg to 5 mcg, 33% of 9 study groups.

Daily doseStudy groups
1 mcg to 2.5 mcg
1
2.5 mcg to 5 mcg
3
5 mcg to 10 mcg
2
10 mcg to 25 mcg
1
25 mcg to 50 mcg
0
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
0
500 mcg to 1 mg
1
1 mg to 2.5 mg
0
2.5 mg to 5 mg
0
5 mg to 10 mg
0
10 mg to 25 mg
1

Commonly used together

9 of 9 study groups took Vitamin D, Zinc and Vitamin B12 with something else. Shown: what 3 or more different studies gave. The 10 most common of 12.

What was given together, not what works together.

Taken withStudy groups
Iron
7
Vitamin A
6
Vitamin B6
6
Vitamin C
6
Copper
5
Folic Acid
5
Vitamin E
5
Iodine
4
Riboflavin
4
Selenium
4

9 study groups

Study
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
5 mcg20 mg2 mcg335 days—
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
10 mcg30 mg2.6 mcg——
Effect of zinc plus multivitamin supplementation on growth in school children
2016 · Chelated zinc plus multivitamins · Healthy Thai schoolchildren aged 4–13 years
200 IU20 mg10 mcg26 weeks70
Effects of Low-Dose Dairy Protein Plus Micronutrient Supplementation during Resistance Exercise on Muscle Mass and Physical Performance in Older Adults: A Randomized, Controlled Trial
2018 · ExPM (resistance exercise plus low-dose dairy protein and micronutrient supplementation) · Adults aged 65–80 years, non-disabled and not exercising regularly
5 mcg8 mg12 mcg12 weeks40
A prospective randomized comparative trial evaluating postoperative nutritional intervention in patients with oral cancer
2022 · Intervention group · Adults with oral cancer after surgery; ages 18 and older, both sexes
2,857 IU40 mg1 mg26 weeks22
Effects of Macuprev(®) Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up
2019 · AMD-M group · Adults with intermediate age-related macular degeneration; 9 male and 21 female enrolled overall, mean age 69.32 years
800 IU16 mg18 mg26 weeks15
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
10 mcg10 mg5.2 mcg—870
Antenatal Multiple Micronutrient Supplementation Compared to Iron-Folic Acid Affects Micronutrient Status but Does Not Eliminate Deficiencies in a Randomized Controlled Trial Among Pregnant Women of Rural Bangladesh
2019 · MM · Pregnant women aged 12–45 years in rural Bangladesh
5 mcg12 mg2.6 mcg165 days749
Newborn micronutrient status biomarkers in a cluster-randomized trial of antenatal multiple micronutrient compared with iron folic acid supplementation in rural Bangladesh
2020 · MM · Pregnant women in rural Bangladesh; age range not specified; no disease condition specified
5 mcg12 mg2.6 mcg—176
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