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Vitamin D and Calcium: study protocols

103 study groups took Vitamin D together with Calcium. These are the doses the studies gave. They are not a recommendation.

Vitamin D: what the research found →

Dose per serving from research: Vitamin D

86 study groups in 58 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 IU to 500 IU, 47% of 86 study groups.

Daily doseStudy groups
250 IU or less
4
250 IU to 500 IU
40
500 IU to 1,000 IU
32
1,000 IU to 2,500 IU
5
2,500 IU to 5,000 IU
4
over 5,000 IU
1

Dose per serving from research: Calcium

96 study groups in 66 studies say how much Calcium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 48% of 96 study groups.

Daily doseStudy groups
250 mg or less
1
250 mg to 500 mg
18
500 mg to 1 g
46
1 g to 2.5 g
27
over 2.5 g
4

Commonly used together

18 of 103 study groups took Vitamin D and Calcium with something else, but nothing that 3 or more different studies gave.

103 study groups

Study
Urinary tract stone occurrence in the Women's Health Initiative (WHI) randomized clinical trial of calcium and vitamin D supplements
2011 · CaD group · Postmenopausal women aged 50–79 years
400 IU1 g7 years18,176
Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study
2013 · Calcium plus vitamin D (CaD) group · Postmenopausal women aged 50–79 years
400 IU1 g7 years18,176
A Randomized Trial of Calcium Plus Vitamin D Supplementation and Risk of Ductal Carcinoma In Situ of the Breast
2021 · calcium plus vitamin D · Postmenopausal women aged 50–79 years at enrollment
400 IU1 g2592 days18,176
Incidence of hematologic malignancy and cause-specific mortality in the Women's Health Initiative randomized controlled trial of calcium and vitamin D supplementation
2017 · active treatment · older women; median age 63 years
400 IU1 g7 years18,141
Risk of heart failure among postmenopausal women: a secondary analysis of the randomized trial of vitamin D plus calcium of the women's health initiative
2015 · intervention group · Postmenopausal women aged 50–79 years, free of heart failure at baseline, with and without pre-existing cardiovascular risk conditions
400 IU1 g2577 days18,023
Vitamin D and calcium supplementation prevents osteoporotic fractures in elderly community dwelling residents: a pragmatic population-based 3-year intervention study
2004 · Calcium and Vitamin D Program · Community-dwelling residents aged 66 years and older
400 IU1 g3 years4,957
Multivitamin and mineral supplementation is associated with the reduction of fracture risk and hospitalization rate in Chinese adult males: a randomized controlled study
2015 · supplement group — women · Women aged 40–69 with esophageal squamous dysplasia (ESD) in Linxian, China
20 mcg324 mg6 years927
Multivitamin and mineral supplementation is associated with the reduction of fracture risk and hospitalization rate in Chinese adult males: a randomized controlled study
2015 · supplement group — men · Men aged 40–69 with esophageal squamous dysplasia (ESD) in Linxian, China
20 mcg324 mg6 years726
Prevention of benign paroxysmal positional vertigo with vitamin D supplementation: A randomized trial
2020 · intervention · Patients with confirmed benign paroxysmal positional vertigo (BPPV); supplementation was given when serum vitamin D was below 20 ng/mL
800 IU1 g1 year518
Calcium and vitamin D supplementation and increased risk of serrated polyps: results from a randomised clinical trial
2019 · calcium and vitamin D · Adults aged 45–75 with at least one adenomatous polyp detected and removed within the preceding 4 months
1,000 IU1.2 g5 years421