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Vitamin C, Vitamin E, Selenium and Zinc: study protocols

8 study groups took Vitamin C together with Vitamin E, Selenium and Zinc. These are the doses the studies gave. They are not a recommendation.

Vitamin C: what the research found →

Dose per serving from research: Vitamin C

8 study groups in 8 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 88% of 8 study groups.

Daily doseStudy groups
50 mg or less
1
50 mg to 100 mg
0
100 mg to 250 mg
7

Dose per serving from research: Vitamin E

8 study groups in 8 studies say how much Vitamin E participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 63% of 8 study groups.

Daily doseStudy groups
10 mg or less
1
10 mg to 25 mg
2
25 mg to 50 mg
5

Dose per serving from research: Selenium

6 study groups in 6 studies say how much Selenium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mcg to 100 mcg, 83% of 6 study groups.

Daily doseStudy groups
25 mcg or less
1
25 mcg to 50 mcg
0
50 mcg to 100 mcg
5

Dose per serving from research: Zinc

8 study groups in 8 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 10 mg to 25 mg, 88% of 8 study groups.

Daily doseStudy groups
10 mg or less
1
10 mg to 25 mg
7

Commonly used together

8 of 8 study groups took Vitamin C, Vitamin E, Selenium and Zinc with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Beta-Carotene
7

8 study groups

Study
The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals
2004 · antioxidant supplement group · French women aged 35–60 and men aged 45–60 in the general population
120 mg30 mg100 mcg20 mg2739 days—
Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels?
2005 · daily antioxidant supplementation · French adults: women aged 35–60 years and men aged 45–60 years
120 mg30 mg100 mcg20 mg2739 days—
Antioxidant supplementation increases the risk of skin cancers in women but not in men
2007 · antioxidant group · French adult women and men in a general-population primary-prevention trial
120 mg30 mg—20 mg2738 days—
Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: a double masked, randomized, controlled trial
2010 · Micronutrient-fortified milk (MN group) · Children aged 1–4 years in India; many had anemia, iron deficiency, or growth faltering
40.2 mg7.5 mg4.2 mcg7.8 mg1 year316
Effect of two years' supplementation with natural antioxidants on vitamin and trace element status biomarkers: preliminary data of the SU.VI.MAX study
2001 · Antioxidant supplementation group · Women aged 35–60 years and men aged 45–60 years in France, general population
120 mg30 mg100 mcg20 mg2 years—
Effect of 6 month supplementation with different combinations of an association of antioxidant nutrients on biochemical parameters and markers of the antioxidant defence system in the elderly. The Geriatrie/Min.Vit.Aox Network
1996 · VT (vitamins associated with trace elements) · Elderly nursing-home residents aged 65–103 years who were long-term hospitalized
120 mg15 mg100 mcg20 mg26 weeks—
Effects of trace element and/or vitamin supplementation on vitamin and mineral status, free radical metabolism and immunological markers in elderly long term-hospitalized subjects. Geriatric Network MIN. VIT. AOX
1997 · trace elements associated with vitamins · Institutionalized elderly subjects in long-term hospital or nursing-home care
120 mg15 mg—20 mg1 year—
Effects of supplementation with a combination of antioxidant vitamins and trace elements, at nutritional doses, on biochemical indicators and markers of the antioxidant system in adult subjects
1998 · supplementation group · Adult men aged 45–60 years and women aged 35–60 years
120 mg30 mg100 mcg20 mg26 weeks—