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Vitamin C, Vitamin B6, Zinc and Vitamin B12: study protocols

7 study groups took Vitamin C together with Vitamin B6, Zinc and Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Vitamin C: what the research found →

Dose per serving from research: Vitamin C

7 study groups in 6 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg, 43% of 7 study groups.

Daily doseStudy groups
50 mg or less
1
50 mg to 100 mg
1
100 mg to 250 mg
3
250 mg to 500 mg
2

Dose per serving from research: Vitamin B6

7 study groups in 6 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 43% of 7 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
3
2.5 mg to 5 mg
2
5 mg to 10 mg
2

Dose per serving from research: Zinc

7 study groups in 6 studies say how much Zinc participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mg to 10 mg and 10 mg to 25 mg, 43% of 7 study groups each.

Daily doseStudy groups
5 mg to 10 mg
3
10 mg to 25 mg
3
25 mg to 50 mg
1

Dose per serving from research: Vitamin B12

7 study groups in 6 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mcg to 2.5 mcg, 43% of 7 study groups.

Daily doseStudy groups
1 mcg to 2.5 mcg
3
2.5 mcg to 5 mcg
2
5 mcg to 10 mcg
2

Commonly used together

7 of 7 study groups took Vitamin C, Vitamin B6, Zinc and Vitamin B12 with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Folic Acid
5
Vitamin E
5
Vitamin D
4
Magnesium
3
Riboflavin
3
Thiamine
3

7 study groups

Study
Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males
2010 · multi-vitamin/mineral · Healthy males aged 30–55 years in full-time employment
500 mg10 mg10 mg10 mcg33 days103
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
50 mg1.7 mg20 mg2 mcg335 days—
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
100 mg2.2 mg30 mg2.6 mcg——
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
2011 · Group MVB · Patients with type 2 diabetes
200 mg10 mg20 mg10 mcg120 days—
Effects of Multivitamin, Multimineral and Phytonutrient Supplementation on Nutrient Status and Biomarkers of Heart Health Risk in a Russian Population: A Randomized, Double Blind, Placebo Controlled Study
2018 · VMP (Nutrilite Double X™) · Generally healthy adults aged 40–70 years in Moscow with low habitual recommended-food intake (recommended food score <12), predominantly women; no chronic diseases
180 mg3 mg6 mg2 mcg8 weeks60
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG1 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
135 mg2.1 mg7.5 mg2.5 mcg12 weeks30
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG2 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
270 mg4.2 mg15 mg5 mcg6 weeks30
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