Vitamin C, Vitamin B6, Vitamin B12 and Vitamin E: study protocols
6 study groups took Vitamin C together with Vitamin B6, Vitamin B12 and Vitamin E. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin C
6 study groups in 5 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 100 mg to 250 mg and 250 mg to 500 mg, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 50 mg or less | 1 |
| 50 mg to 100 mg | 1 |
| 100 mg to 250 mg | 2 |
| 250 mg to 500 mg | 2 |
Dose per serving from research: Vitamin B6
6 study groups in 5 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mg to 2.5 mg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 1 mg to 2.5 mg | 3 |
| 2.5 mg to 5 mg | 1 |
| 5 mg to 10 mg | 1 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 1 |
Dose per serving from research: Vitamin B12
6 study groups in 5 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 1 mcg to 2.5 mcg and 2.5 mcg to 5 mcg, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 1 mcg to 2.5 mcg | 2 |
| 2.5 mcg to 5 mcg | 2 |
| 5 mcg to 10 mcg | 1 |
| 10 mcg to 25 mcg | 0 |
| 25 mcg to 50 mcg | 0 |
| 50 mcg to 100 mcg | 0 |
| 100 mcg to 250 mcg | 0 |
| 250 mcg to 500 mcg | 1 |
Dose per serving from research: Vitamin E
5 study groups in 4 studies say how much Vitamin E participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 5 mg to 10 mg and 50 mg to 100 mg, 40% of 5 study groups each.
| Daily dose | Study groups |
|---|---|
| 5 mg to 10 mg | 2 |
| 10 mg to 25 mg | 0 |
| 25 mg to 50 mg | 1 |
| 50 mg to 100 mg | 2 |
Commonly used together
6 of 6 study groups took Vitamin C, Vitamin B6, Vitamin B12 and Vitamin E with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Folic Acid | 5 |
| Zinc | 5 |
| Riboflavin | 4 |
| Vitamin D | 4 |
| Thiamine | 3 |
6 study groups
| Study | ||||||
|---|---|---|---|---|---|---|
| Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren 2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified | 50 mg | 1.7 mg | 2 mcg | 8 mg | 335 days | — |
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 100 mg | 2.2 mg | 2.6 mcg | 10 mg | — | — |
| Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation 2011 · Group MVB · Patients with type 2 diabetes | 200 mg | 10 mg | 10 mcg | 100 mg | 120 days | — |
| Antioxidant supplementation with or without B-group vitamins after acute ischemic stroke: a randomized controlled trial 2006 · Antioxidant vitamins plus B-group vitamins · Acute ischemic stroke patients treated within 12 hours of symptom onset | 500 mg | 50 mg | 400 mcg | 800 IU | 2 weeks | 24 |
| Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study 2022 · TG1 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions | 135 mg | 2.1 mg | 2.5 mcg | 45 mg | 12 weeks | 30 |
| Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study 2022 · TG2 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions | 270 mg | 4.2 mg | 5 mcg | 90 mg | 6 weeks | 30 |