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Vitamin C, Vitamin B6, Folic Acid and Vitamin E: study protocols

6 study groups took Vitamin C together with Vitamin B6, Folic Acid and Vitamin E. These are the doses the studies gave. They are not a recommendation.

Vitamin C: what the research found →

Dose per serving from research: Vitamin C

6 study groups in 5 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 50 mg to 100 mg and 100 mg to 250 mg and 250 mg to 500 mg, 33% of 6 study groups each.

Daily doseStudy groups
50 mg to 100 mg
2
100 mg to 250 mg
2
250 mg to 500 mg
2

Dose per serving from research: Vitamin B6

6 study groups in 5 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 33% of 6 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
2
2.5 mg to 5 mg
1
5 mg to 10 mg
1
10 mg to 25 mg
1
25 mg to 50 mg
1

Dose per serving from research: Folic Acid

6 study groups in 5 studies say how much Folic Acid participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg and 500 mcg to 1 mg, 33% of 6 study groups each.

Daily doseStudy groups
100 mcg to 250 mcg
1
250 mcg to 500 mcg
2
500 mcg to 1 mg
2
1 mg to 2.5 mg
0
2.5 mg to 5 mg
1

Commonly used together

6 of 6 study groups took Vitamin C, Vitamin B6, Folic Acid and Vitamin E with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Vitamin B12
5
Zinc
4
Riboflavin
3

6 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
100 mg2.2 mg400 mcg10 mg——
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
2011 · Group MVB · Patients with type 2 diabetes
200 mg10 mg1 mg100 mg120 days—
Supplementation with antioxidant micronutrients in pregnant women with obesity: a randomized controlled trial
2024 · Intervention group · Pregnant women with obesity (BMI ≥30 kg/m²)
90 mg18 mg800 mcg——64
Antioxidant supplementation with or without B-group vitamins after acute ischemic stroke: a randomized controlled trial
2006 · Antioxidant vitamins plus B-group vitamins · Acute ischemic stroke patients treated within 12 hours of symptom onset
500 mg50 mg5 mg800 IU2 weeks24
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG1 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
135 mg2.1 mg200 mcg45 mg12 weeks30
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG2 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
270 mg4.2 mg400 mcg90 mg6 weeks30
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