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Vitamin C and Vitamin B6: study protocols

13 study groups took Vitamin C together with Vitamin B6. These are the doses the studies gave. They are not a recommendation.

Vitamin C: what the research found →

Dose per serving from research: Vitamin C

13 study groups in 12 studies say how much Vitamin C participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 100 mg to 250 mg and 250 mg to 500 mg, 31% of 13 study groups each.

Daily doseStudy groups
25 mg to 50 mg
2
50 mg to 100 mg
2
100 mg to 250 mg
4
250 mg to 500 mg
4
500 mg to 1 g
0
1 g to 2.5 g
1

Dose per serving from research: Vitamin B6

13 study groups in 12 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 31% of 13 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
4
2.5 mg to 5 mg
3
5 mg to 10 mg
2
10 mg to 25 mg
1
25 mg to 50 mg
1
50 mg to 100 mg
2

Commonly used together

13 of 13 study groups took Vitamin C and Vitamin B6 with something else. Shown: what 3 or more different studies gave. The 10 most common of 11.

What was given together, not what works together.

Taken withStudy groups
Vitamin B12
10
Folic Acid
8
Vitamin E
8
Zinc
8
Riboflavin
4
Vitamin D
4
vitamin B2
4
Magnesium
3
Niacin
3
Thiamine
3

13 study groups

Study
Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males
2010 · multi-vitamin/mineral · Healthy males aged 30–55 years in full-time employment
500 mg10 mg33 days103
Megadose vitamins in bladder cancer: a double-blind clinical trial
1994 · megadose vitamins arm · Patients with biopsy-confirmed transitional cell carcinoma of the bladder receiving BCG immunotherapy
2 g100 mg—35
Effects of multimicronutrient supplementation on helminth reinfection: a randomized, controlled trial in Kenyan schoolchildren
2003 · multimicronutrient supplementation · Schoolchildren in Nyanza Province, Kenya; age and sex not specified
50 mg1.7 mg335 days—
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
100 mg2.2 mg——
Combination of Chemically Characterized Pomegranate Extract and Hydrophilic Vitamins against Prolonged Fatigue: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
2023 · Group 2 (food supplement) · Adults aged 18–75 years, either sex, with mild-to-moderate prolonged fatigue
200 mg4 mg8 weeks29
Improving neuropathy scores in type 2 diabetic patients using micronutrients supplementation
2011 · Group MVB · Patients with type 2 diabetes
200 mg10 mg120 days—
Low-dose B vitamins supplementation ameliorates cardiovascular risk: a double-blind randomized controlled trial in healthy Chinese elderly
2015 · treatment group · Healthy adults aged 60–74 years
50 mg2 mg1 year—
Supplementation with antioxidant micronutrients in pregnant women with obesity: a randomized controlled trial
2024 · Intervention group · Pregnant women with obesity (BMI ≥30 kg/m²)
90 mg18 mg—64
Effects of Multivitamin, Multimineral and Phytonutrient Supplementation on Nutrient Status and Biomarkers of Heart Health Risk in a Russian Population: A Randomized, Double Blind, Placebo Controlled Study
2018 · VMP (Nutrilite Double X™) · Generally healthy adults aged 40–70 years in Moscow with low habitual recommended-food intake (recommended food score <12), predominantly women; no chronic diseases
180 mg3 mg8 weeks60
Antioxidant supplementation with or without B-group vitamins after acute ischemic stroke: a randomized controlled trial
2006 · Antioxidant vitamins plus B-group vitamins · Acute ischemic stroke patients treated within 12 hours of symptom onset
500 mg50 mg2 weeks24
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG1 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
135 mg2.1 mg12 weeks30
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study
2022 · TG2 · Hospitalized adults older than 65 years; sex not restricted; recruited for causes other than cancer, with specified immune-disease and infection exclusions
270 mg4.2 mg6 weeks30
Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen
2008 · group C · Middle-aged women with low bone mineral density (osteopaenia)
500 mg75 mg1 year20
Vitamin C and Vitamin B6: study protocols | supp.fit