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Vitamin B6, Vitamin D, Vitamin B12 and Riboflavin: study protocols

5 study groups took Vitamin B6 together with Vitamin D, Vitamin B12 and Riboflavin. These are the doses the studies gave. They are not a recommendation.

Vitamin B6: what the research found →

Dose per serving from research: Vitamin B6

5 study groups in 4 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 60% of 5 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
3
2.5 mg to 5 mg
1
5 mg to 10 mg
1

Dose per serving from research: Vitamin D

5 study groups in 4 studies say how much Vitamin D participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 5 mcg to 10 mcg, 60% of 5 study groups.

Daily doseStudy groups
2.5 mcg to 5 mcg
2
5 mcg to 10 mcg
3

Dose per serving from research: Vitamin B12

5 study groups in 4 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mcg to 2.5 mcg and 5 mcg to 10 mcg, 40% of 5 study groups each.

Daily doseStudy groups
1 mcg to 2.5 mcg
2
2.5 mcg to 5 mcg
1
5 mcg to 10 mcg
2

Dose per serving from research: Riboflavin

5 study groups in 4 studies say how much Riboflavin participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 1 mg to 2.5 mg, 80% of 5 study groups.

Daily doseStudy groups
1 mg to 2.5 mg
4
2.5 mg to 5 mg
1

Commonly used together

5 of 5 study groups took Vitamin B6, Vitamin D, Vitamin B12 and Riboflavin with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Iron
4
Folic Acid
3

5 study groups

Study
Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal
2003 · Multiple micronutrients · Pregnant women in rural Nepal
2.2 mg10 mcg2.6 mcg1.8 mg——
A 2-Year Randomized Controlled Trial With Low-Dose B-Vitamin Supplementation Shows Benefits on Bone Mineral Density in Adults With Lower B12 Status
2022 · B-vitamin treatment · Community-dwelling adults aged 50 years or older; men and women; no specific diagnosed condition, and not currently taking B-vitamin supplements at screening
10 mg10 mcg10 mcg5 mg2 years103
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
2.6 mg10 mcg5.2 mcg1.8 mg—870
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, morning · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
1.74 mg4.15 mcg1.45 mcg1.71 mg12 weeks18
Fortified breakfast cereal consumed daily for 12 wk leads to a significant improvement in micronutrient intake and micronutrient status in adolescent girls: a randomised controlled trial
2016 · Fortified cereal, evening · Females aged 16–19 years who regularly skipped breakfast and had low riboflavin status and haemoglobin; no diagnosed illness
1.74 mg4.15 mcg1.45 mcg1.71 mg12 weeks16