Vitamin B6, Vitamin B12, Folic Acid and Vitamin C: study protocols
6 study groups took Vitamin B6 together with Vitamin B12, Folic Acid and Vitamin C. These are the doses the studies gave. They are not a recommendation.
Dose per serving from research: Vitamin B6
6 study groups in 4 studies say how much Vitamin B6 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 500 mcg to 1 mg and 1 mg to 2.5 mg and 10 mg to 25 mg, 33% of 6 study groups each.
| Daily dose | Study groups |
|---|---|
| 500 mcg to 1 mg | 2 |
| 1 mg to 2.5 mg | 2 |
| 2.5 mg to 5 mg | 0 |
| 5 mg to 10 mg | 0 |
| 10 mg to 25 mg | 2 |
Dose per serving from research: Vitamin B12
6 study groups in 4 studies say how much Vitamin B12 participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 2.5 mcg to 5 mcg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 2.5 mcg to 5 mcg | 3 |
| 5 mcg to 10 mcg | 1 |
| 10 mcg to 25 mcg | 0 |
| 25 mcg to 50 mcg | 2 |
Dose per serving from research: Folic Acid
6 study groups in 4 studies say how much Folic Acid participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 250 mcg to 500 mcg, 67% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 250 mcg to 500 mcg | 4 |
| 500 mcg to 1 mg | 2 |
Dose per serving from research: Vitamin C
6 study groups in 4 studies say how much Vitamin C participants took a day.
These are the doses the studies gave. They are not a recommendation.
Most common: 50 mg to 100 mg, 50% of 6 study groups.
| Daily dose | Study groups |
|---|---|
| 50 mg or less | 1 |
| 50 mg to 100 mg | 3 |
| 100 mg to 250 mg | 0 |
| 250 mg to 500 mg | 2 |
Commonly used together
5 of 6 study groups took Vitamin B6, Vitamin B12, Folic Acid and Vitamin C with something else. Shown: what 3 or more different studies gave.
What was given together, not what works together.
| Taken with | Study groups |
|---|---|
| Vitamin E | 5 |
6 study groups
| Study | ||||||
|---|---|---|---|---|---|---|
| Effects of maternal micronutrient supplementation on fetal loss and infant mortality: a cluster-randomized trial in Nepal 2003 · Multiple micronutrients · Pregnant women in rural Nepal | 2.2 mg | 2.6 mcg | 400 mcg | 100 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin plus vitamin A · HIV-positive pregnant Tanzanian women | 25 mg | 50 mcg | 800 mcg | 500 mg | — | — |
| Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension 2005 · Multivitamin without vitamin A · HIV-positive pregnant Tanzanian women | 25 mg | 50 mcg | 800 mcg | 500 mg | — | — |
| Low-dose B vitamins supplementation ameliorates cardiovascular risk: a double-blind randomized controlled trial in healthy Chinese elderly 2015 · treatment group · Healthy adults aged 60–74 years | 2 mg | 10 mcg | 400 mcg | 50 mg | 1 year | — |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active group (RCT1, RCT2 and RCT3) · Men and women aged 50 years or older with mild or mild-to-moderate Alzheimer's disease; RCT3 participants were on stable approved Alzheimer's medication, while RCT1 and RCT2 participants were drug-free for Alzheimer's medication. | 1 mg | 3 mcg | 400 mcg | 80 mg | 24 weeks | 501 |
| Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease 2015 · Active product during open-label extension (OLE) · Men and women aged 50 years or older with mild Alzheimer's disease who completed RCT2. | 1 mg | 3 mcg | 400 mcg | 80 mg | 24 weeks | 201 |