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Vitamin B6, Calcium, Vitamin D and Vitamin B12: study protocols

6 study groups took Vitamin B6 together with Calcium, Vitamin D and Vitamin B12. These are the doses the studies gave. They are not a recommendation.

Vitamin B6: what the research found →

Dose per serving from research: Vitamin B6

6 study groups in 6 studies say how much Vitamin B6 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 25 mg to 50 mg, 67% of 6 study groups.

Daily doseStudy groups
1 mg or less
1
1 mg to 2.5 mg
0
2.5 mg to 5 mg
1
5 mg to 10 mg
0
10 mg to 25 mg
0
25 mg to 50 mg
4

Dose per serving from research: Calcium

6 study groups in 6 studies say how much Calcium participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 500 mg to 1 g, 50% of 6 study groups.

Daily doseStudy groups
100 mg to 250 mg
1
250 mg to 500 mg
2
500 mg to 1 g
3

Dose per serving from research: Vitamin B12

6 study groups in 6 studies say how much Vitamin B12 participants took a day.

These are the doses the studies gave. They are not a recommendation.

Most common: 250 mcg to 500 mcg, 67% of 6 study groups.

Daily doseStudy groups
5 mcg to 10 mcg
2
10 mcg to 25 mcg
0
25 mcg to 50 mcg
0
50 mcg to 100 mcg
0
100 mcg to 250 mcg
0
250 mcg to 500 mcg
4

Commonly used together

6 of 6 study groups took Vitamin B6, Calcium, Vitamin D and Vitamin B12 with something else. Shown: what 3 or more different studies gave.

What was given together, not what works together.

Taken withStudy groups
Folic Acid
5

6 study groups

Study
Maternal B-vitamin and vitamin D status before, during, and after pregnancy and the influence of supplementation preconception and during pregnancy: Prespecified secondary analysis of the NiPPeR double-blind randomized controlled trial
2023 · intervention · Women planning pregnancy; generally healthy, recruited before conception
2.6 mg150 mg10 mcg5.2 mcg—870
Mineral water fortified with folic acid, vitamins B6, B12, D and calcium improves folate status and decreases plasma homocysteine concentration in men and women
2004 · Fortified mineral water · Free-living men and women without folate deficiency or elevated homocysteine
1 mg563 mg0.6 mcg7.5 mcg8 weeks—
Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers
2018 · D + Ca + B · Adults, mean age 68.4 years; no specific condition stated
50 mg800 mg—500 mcg1 year32
Plasma trimethylamine-N-oxide following supplementation with vitamin D or D plus B vitamins
2017 · vitamin D + B arm · Participants; age, sex, and health condition not specified
50 mg800 mg1,200 IU500 mcg1 year25
One year B and D vitamins supplementation improves metabolic bone markers
2013 · group A · Healthy adults older than 54 years
50 mg456 mg1,200 IU500 mcg1 year—
One-carbon metabolites and telomere length in a prospective and randomized study of B- and/or D-vitamin supplementation
2017 · group A · Adults older than 54 years; no specific condition stated
50 mg456 mg1,200 IU500 mcg1 year—
Vitamin B6, Calcium, Vitamin D and Vitamin B12: study protocols | supp.fit